木香超临界提取物抗实验性胃溃疡的研究  

Study of the Effect of Exceed Critical Extracts from Radix Aucklandiae on Experimental Gastric Ulcer Model

作　　者：韩坚[1] 林煌权[1] 钟志勇[1] 荣向路[1] 

机构地区：[1]广州中医药大学中药学院,广州510405

出　　处：《中药材》2005年第11期1017-1019,共3页Journal of Chinese Medicinal Materials

摘　　要：目的:通过实验探讨木香超临界提取物对多种实验性胃溃疡模型的影响.方法:观察木香超临界提取物对大鼠盐酸-乙醇型急性胃溃疡、小鼠利血平型胃溃疡和大鼠醋酸损伤型慢性胃溃疡模型的作用.结果:木香超临界提取物对盐酸-乙醇型急性胃溃疡具有显著的抑制作用(P＜0.01);对小鼠利血平型胃溃疡和大鼠醋酸损伤型慢性胃溃疡均有明显的抑制作用(P＜0.05～0.01).Objective： To study the effect of exceed critical extracts from Radix Aucklandiae （ MXY for short） on many kinds of experimental gastric ulcer model. Methods： The effect of MXY to the mice＇ s gastric ulcer induced by hydrochloric acid-ethanol, reserpine, and chronic gastric ulcer induced by acetic acid were observed. Results： Compared with model group, MXY had remarkable inhibition activity on the hydrochloirc acid-ethanol type acute gastric ulcer（ P 〈 0. 01 ）. It also could obviously reduce the index of gastric ulcer induced by reserpine and chronic gastric ulcer induced by acetic acid（ P 〈0. 05 - 0. 01 ）.

关 键 词：木香 胃溃疡 药理作用 

分 类 号：R573.102[医药卫生—消化系统] R284.1[医药卫生—内科学]