慢性浅表性胃炎的组织病理学分析——附120例报告  

Histopathological analysis of gastric mucosa in chronic superficial gastritis

作　　者：苏红[1] 陈其奎[1] 钟英强[1] 夏忠胜[1] 黄开红[1] 王凌云[1] 幸连春[1] 曾志勇[1] 黄志青[1] 

机构地区：[1]中山大学附属第二医院消化科,510120

出　　处：《新医学》2005年第12期694-695,737,共3页Journal of New Medicine

摘　　要：目的:从病理学角度分析120例幽门螺杆菌阳性慢性浅表性胃炎(chronic superficial gastritis,CSG)的组织学特征。方法:用电子胃镜对确诊的120例幽门螺杆菌阳性CSG患者的炎症活动性、慢性炎症、血管病变、上皮损伤、腺体萎缩、不典型增生及肠化生等组织形态学指标进行回顾性分析。结果:CSG病人的黏膜具有急性炎症、慢性炎症、血管病变、上皮损伤,分别高达97．5％(117／ 120)、98．3％(118／120)、95．8％(115／120)、70％(84／120),腺体萎缩、不典型增生及肠化生的发生率约为35％-39．2％,组织学改变均以1级占多数。结论:急、慢性炎症细胞浸润,血管病变及上皮损伤是幽门螺杆菌阳性CSG的组织学基础,其慢性黏膜病变的组织学改变均以1级为主。Objective： To investigate the histopathological changes of gastric mucosa in chronic superficial gastritis （CSG）. Methods： 120 patients with helicobacter pylori （Hp） positive CSG proven by endoscopy were enrolled into the study. Acute inflammation activity, chronic inflammation, vascular pathological changes, epithelium injury, mucosal atrophy, atypical hyperplasia and intes- tinal metaplasia were observed. Results： Acute and chronic inflammation were found in 117 cases and 118 cases （97.5%, 98.3% ）, vascular pathological changes was found in 115 patients（ 95.8% ）, epithelium injury of gastric mucosa was found in 84 cases （70%）. The rate of mucosal atrophy, atypical hyperplasia and intestinal metaplasia were observed in 35% - 39.2% of patients. Most of them were in grade 1 of changes. Conclusion： Acute and chronic infiltration of inflammatory cells of gatric mucosa, vascular pathological changes, as well as epithelium injury were the main basic histological changes of Hp positive CSG. Mild-grade of mucosal atrophy, atvoical hvDerolasia and intestinal metaolasia were also associated with Hp positive CSG.

关 键 词：慢性浅表性胃炎 病理学 组织学 炎症 血管病变 上皮损伤 腺体萎缩 不典型增生 肠化生 

分 类 号：R573.3[医药卫生—消化系统]