食物中铅及营养素摄入对儿童血铅的影响  

The effect of intake of lead and nutrients on children's blood lead level

作　　者：许萍[1] 莫宝庆[2] 沈小志[1] 徐殿松[1] 

机构地区：[1]南京医科大学临床教学医院鼓楼医院营养科,江苏南京210008 [2]南京医科大学公共卫生学院营养与食品卫生系,江苏南京210029

出　　处：《肠外与肠内营养》2005年第6期341-344,共4页Parenteral & Enteral Nutrition

摘　　要：目的：探讨食物中铅摄入及营养素摄入对儿童血铅的影响。方法：随机选择263名儿童进行血铅测定和膳食调查，并用原子吸收分光光度法测定食物中的铅含量，了解儿童铅及营养素的摄入量。根据血铅值分为高血铅组（≥100μg/L）及低血铅组（〈100μg/L），对比两组食物中铅及营养素摄入量，采用Logistic回归分析各营养素摄入与血铅的相关性。结果：263名儿童血铅平均值为（80．84±42．79）μg/L，其中血铅值≥100μg/L的儿童有55名（20．91％）。食物中铅摄入量范围为3．99～43．9μg/（kg·d），均高于暂定每周摄入量（PTW1），高血铅组儿童铅摄入量较高，但总能量、糖类、纤维素、视黄醇、维生素B1、维生素B2、镁、磷等摄入量相应较低。Logistic回归分析显示，糖类、视黄醇是降低儿童血铅的因素。结论：机体血铅增高可能与铅摄入量较多，总能量、纤维素、维生素B1、B2、镁、磷，尤其是糖类、视黄醇摄入量相应较低有关。Objective： To investigate the effect of intake of lead and nutrients on children g blood lead level. Methods： 263 children aged 9 - 12 y were randomly selected. The children＇s blood lead level and the concentration of lead in foods were measured with atomic absorption spectrum. Food intake was investigated with continuous 3 days recording and the intake of lead and nutrients was then calculated. The children were divided into high blood lead group （ ≥ 100 μg/L）and low blood lead group（ 〈 100 μg/L） according to blood lead levels. The intake of lead and nutrients was compared between the 2 groups. The relationship between the nutrients intake and blood lead levels was evaluated with the Logistic regression analysis. Results： The average level of blood lead was （80.84 ± 42.79 ） μg/L, and there were 55 children whose blood lead level was over 100 μg/L. The range for intake of lead was 3.99 to 43.9 μg/（ kg · d ） , which was over the provisional tolerable weekly intake （ FFWI ）. The intake of lead for children with high blood lead level was significantly higher, but the intake of total energy, carbohydrates, retinol, vitamin B1 ,vitamin B2, magnesium and phosphorus was lower. It was shown in the result of logistic regression analysis that carbohydrates and retinol were the factors which reduced the blood lead level. Conclusion： The increased blood lead level may be related to higher intake of lead and lower intake of total energy, vitamin B1 , vitamin B2, magnesium, phosphorus, especcially carbohydrates and retinol from foods.

关 键 词：铅摄入 血铅 营养素 儿童 

分 类 号：R179[医药卫生—妇幼卫生保健]