气囊扩张术联合肉毒素注射序惯治疗贲门失弛缓症的近期及远期疗效  

Short-term and long-term effect of pneumatic dilation and botulinum toxin injection in treatment of cardiac achalasia

作　　者：弭希峰[1] 黄子成[1] 王木成[1] 李水淼[1] 

机构地区：[1]福建医科大学临床教学医院泉州市第一医院内窥镜科,福建省泉州市362000

出　　处：《世界华人消化杂志》2005年第17期2159-2161,共3页World Chinese Journal of Digestology

摘　　要：目的:探讨气囊扩张术联合A型肉毒素(botulinumtoxinA,BTXA)注射序惯治疗贲门失弛缓症的近期及远期疗效.方法:收集2000-07/2004-05在我院确诊的行内镜下气囊扩张术联合肉毒素注射治疗的贲门失弛缓症患者35例,观察术后1及12mo以上吞咽困难症状改善情况.结果:共35例患者,所有患者术后吞咽困难消失或明显改善,随访1及12mo有效率分别为100%和93.9%.1a失访共2例,复发共3例.结论:气囊扩张术联合内镜下肉毒素注射治疗贲门失弛缓症疗效好,长期疗效稳定,操作安全,有进一步研究应用的前景.AIM： To evaluate the short-term and long-term effect of the pneumatic dilation and botulinum toxin A （BTXA） njection for the cardiac achalasia. METHODS： From July 2000 to May 2004, 35 patients with cardiac achalasia received pneumatic dilation and BTXA injection in our hospital. The improvement of the dysphagia was observed 1 and 12 mo after the treatment. RESULTS： Of the 35 patients, their conditions of dysphagia were significantly improved. The efficacy rates were 100% and 93.9% in the following up （1 and 12 mo, respectively）. Two patients were lost to follow up while dysphagia relapsed in three patients during the following up. CONCLUSION： The pneumatic dilation and BTXA injection for cardiac achalasia is safe, stable and effective in the treatment of cardiac achalasia.

关 键 词：气囊扩张术 A型肉毒素 失弛缓症 

分 类 号：R571[医药卫生—消化系统]