镓盐对骨质疏松大鼠骨组织板层结构影响的实验研究  

Effect of gallium on the rat bone lamellar structure elicited by osteoporosis

作　　者：庞炜[1] 王治伦[2] 周扬[2] 

机构地区：[1]解放军第323医院骨科,西安710054 [2]西安交通大学环境与疾病相关基因教育部重点实验室

出　　处：《中国矫形外科杂志》2005年第23期1801-1802,共2页Orthopedic Journal of China

基　　金：兰州军区医药卫生科研基金资助项目(No.LXH20-11)

摘　　要：[目的]探讨镓盐对大鼠骨质疏松骨组织板层结构的影响。[方法]应用脱钙骨切片观察光镜下骨形态;制作扫描电镜样本,在电镜下观察骨质疏松骨组织板层结构情况。[结果]扫描电镜显示对照组骨排列紧密,呈非常规则的板层状;骨质疏松组骨排列紊乱,结构松散,板层结构有破坏;硝酸镓治疗组骨结构比骨质疏松组规则,排列较整齐、密度较大。[结论]镓盐对骨质疏松引起的骨组织板层结构的损伤有改善作用。[ Objective] To investigate the effect of gallium on the bone lamcllar structure of osteoporosis. [ Method]Microscope was used to observe the bone form. Scanning electron microscope was used to observe the bone lamellar structure. [ Result] The bone lamellar structure of control group ranged regularly and tightly. The sturcture of osteoporosis ranged irregularly and loose. Some were even broken. The structure of gallium nitrate therapy group ranged regularly compared with that of osteoporosis group. [ Conclusion] Gallium can alleviate the damage of lamellar structure elicited by osteoporosis.

关 键 词：镓盐 骨质疏松 扫描电镜 骨 板层结构 

分 类 号：R58[医药卫生—内分泌]