诊断级彩色多普勒对大鼠致突变作用的观察  

The Mutating Effect of Color Doppler Ultrasound of Diagnestic Dosage in Rat

作　　者：朱建平[1] 林坚[1] 张宝珍[1] 朱忠勇[1] 

机构地区：[1]南京军区福州总医院超声诊断科

出　　处：《中华超声影像学杂志》1996年第4期185-187,共3页Chinese Journal of Ultrasonography

摘　　要：本文运用诊断剂量彩色多普勒分组照射孕鼠，观察照射后不同时间点孕鼠遗传学指标的动态变化。结果：１０分钟从内受照组与对照组比较染色体（Ｃｈ）、姐妹染色单体互换（ＳＣＥ）及微核（ＭＮ）无显著性差异，但２０分钟受照组微核数显著增加，在受照后２４小时达峰值，４８小时开始下降，９６小时后恢复正常。表明：诊断剂量彩色多普勒２０分钟照射可造成孕鼠染色体的早期损伤，但机体可通过自身调节修复。The dynamic change of genetic indices in pregnant rats after irradiation by color Doppler ultrasound of diagnostic dose was observated.The result of chromsome(Ch),Sister Chromatid Exchange Fregeguency(SCE) and Micronucleus(MN) showed there were no statistical differences beween the pregnant rats within 10 minutes and control group, but the number of MN of pregnant rats increased markly in 20 minutes irradiation group and arrived to its peak value on 24 hours and recovered after 96 hours.It is suggsted that the chromsome of pregnant rats was damaged early after 20 minutes irradiation,however,it may recover through autoadjustment.

关 键 词：诊断剂量 彩色多普勒 孕鼠 突变效应 

分 类 号：R730.41[医药卫生—肿瘤]