益气活血口服液免疫增强及抗呼吸道病毒实验研究  

EXPERIMENTAL STUDY YIQI HUOXUE ORAL LIQUID ON IMMUNOENHANCEMENT AND ANTIVIRUS FUNCTION

作　　者：夏立红[1] 王明香[2] 康妍萌[1] 张桂菊[1] 张维东[3] 

机构地区：[1]山东中医药大学 [2]山东中医药大学附属医院,山东济南250011 [3]山东省医学科学院,山东济南250062

出　　处：《山东中医药大学学报》2005年第4期306-309,共4页Journal of Shandong University of Traditional Chinese Medicine

基　　金：山东省自然科学基金资助项目(Y2001C20)

摘　　要：目的:研究益气活血口服液的免疫增强作用、对常见呼吸道病毒的抑制作用。方法:随机分组测定益气活血口服液对小鼠碳粒廓清指数的影响、对环磷酰胺致免疫功能低下小鼠脾淋巴细胞转化功能及NK细胞杀伤活性的影响、对正常小鼠溶血素水平的影响及MID实验及体外抗病毒抑菌实验。结果:益气活血口服液可增强巨噬细胞吞噬功能、脾淋巴细胞转化功能及NK细胞杀伤活性,明显增加正常小鼠溶血素水平;经鼠灌胃给药MID大于30g/kg体重,未发现明显不良反应。结论:益气活血口服液有明显的免疫增强作用,对小儿常见呼吸道病毒、细菌均有一定的抑制作用。Objective： to study the immunoenhancement and antivirus function of yiqi h uoxue oral liquid . Methods： determine the index of charcoal clearance, the transformation efficiency of lymphocytic cells of spleen of low immune mice caused by cyclophosphamid, and NK cells activity, the level of hemolysin is also determined. At the same time carry out the external antivirus and antibiotic experiment. Results： the yiqi h uoxue oral liquid can improve the phagolytic function of macrophage, enhance transformation efficiency of lymphocytic cells of spleen and NK cells activity. It can also obviously improve the level of hemolysin. Conclusion： the yiqi huoxue oral liquid has significant immunoenhancement function, it also has antivirus function and antibiotic function.

关 键 词：益气活血口服液 免疫增强 抗病毒 抑菌 实验研究 

分 类 号：R285.5[医药卫生—中药学]