贲门癌术前大剂量放疗与单纯手术的临床研究  

A Study of Comparing Pre-operation Large Dose Irradiation with Surgery alone in the Treatment of Cardia Carcinoma

作　　者：吕桂泉[1] 周星明[1] 陈奇勋[1] 谢尚闹[1] 陈秀勇[1] 郑晓[1] 郭金水[1] 朱永红[1] 

机构地区：[1]浙江省肿瘤医院,杭州310022

出　　处：《浙江肿瘤》1996年第2期97-98,共2页

摘　　要：1987年3月至1991年10月对66例贲门癌随机分组治疗，术前放疗和单纯手术各33例。术前放疗组在术前接受照射5天，共5次25Gy后，体息1～3周后手术，观察术中出血量、手术时间、术中输血量、术后并发症、创口愈合情况，其结果与单纯手术组相同．术前放疗组切除率为88％（29／33），单纯手术组为70％（23／33），P＜0．05．近期疗效术前放疗组1年、3年生存率为76％（25／33）、48％（16／33），而单纯手术组为52％（17／33）、24％（8／33），呈显著性差异。两组5年生存率各为21％（6／28）与14％（4／28），P＞0．05，无统计学意义．提示术前大剂量放方能提高贲门癌手术切除率和近期疗效．66 cases of cardia carcinoma were treated from March, 1987 to October, 1991. The patients were divided into two group-s: Group Ⅰ (33 cases) was treated by pre-operative radiotherapy (25Gy/5f in five days), then followed by surgery with an interval of 1 ~3 weeks. Group Ⅱ (33 cases) was treated by surgery alone. There was no difference between the two groups in bleeeding quantity during operation, operation duration, postoperation complications and healing rate of wound. The 1 ~and 3~ year survival rates were 76 % (25 /33) in Group Ⅰ, 52 % (17/33) and 24% (8/33 ) Ⅱ Group Ⅱ respectively (P<0.05 ). The 5 ~year survival rates was 21%(6/28) in Group Ⅰ and 14% (4/28) in Group Ⅱ (P>0. 05). The authors believe that the treatment result of Group Ⅰ is better than that of Group,Ⅱ

关 键 词：贲门癌 手术前 放射疗法 

分 类 号：R735[医药卫生—肿瘤]