肠外高营养治疗重症溃疡性结肠炎119例分析  

Clinical Analysis of Parenteral Hyperalimentation in 119 Severe Ulcerative Colitis Patients

作　　者：许昌泰[1] 郭学刚[2] 孙安华[2] 李彩宁[2] 张宏博[2] 周新民[2] 潘伯荣[2] 

机构地区：[1]第四军医大学学报编辑部,710032 [2]西京医院全军消化病研究所

出　　处：《天津医药》2005年第12期762-764,共3页Tianjin Medical Journal

基　　金：陕西省卫生厅基金资助项目(项目编号:2004D26)

摘　　要：目的:观察肠外高营养对重症溃疡性结肠炎临床治疗效果。方法:对119例重症溃疡性结肠炎患者采取肠外静脉补充足够的营养,完全胃肠道休息。同时于治疗前后进行组织学检查。结果:经过4周治疗后临床痊愈36例(30.3%),好转65例(54.6%),无效18例(15.1%),总有效率84.9%。全部患者血清谷草转氨酶和谷丙转氨酶在正常范围,血清白蛋白治疗后明显好转(P<0.05),组织学也明显改善。结论:重症溃疡性结肠炎肠外静脉高营养疗法是一种安全、有效可行的方法,同时可以促进组织学恢复。Objective： To study the clinical effects of parenteral hyperalimentation in severe ulcerative colitis patients. Methods： Parenteral hyperalimentation and complete gastrointestinal tract rest were given in 119 severe ulcerative colitis patients, and the histology examinations were studied before and after therapy. Results： After 4 weeks＇ therapy, 36 cases fully recovered （30.3%）, 65 cases improved （54.6%）, 18 cases inefficient （15.1%）, and the total effective rate was 84.9%. Serum aspartate aminotransferase （AST） and alanine aminotransferase （ALT） were in common range in all patients, the serum albumin significantly increased （P 〈 0.05）, and the histology significantly improved. Conclusion： The parenteral hyperalimentation therapy is a safe and effective method for severe ulcerative colitis patients, and it can improve the histology of patients.

关 键 词：胃肠外营养 全 结肠炎 溃疡性 危重病 

分 类 号：R574.62[医药卫生—消化系统] R563.05[医药卫生—内科学]