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作 者:郭榆江[1] 刘晓[1] 黄燮民[1] 陶国清[1]
机构地区:[1]南京医科大学附属无锡第一医院普外科,无锡,214002
出 处:《中国现代手术学杂志》2005年第5期360-361,共2页Chinese Journal of Modern Operative Surgery
摘 要:目的探讨双侧原发性乳腺癌(bilateral primary breast cancer,BPBC)的诊断、治疗及预后。方法回顾性分析25例BPBC的临床资料,其中同时性BPBC4例,异时性21例,均行根治或改良根治术,术后均行CMF或CAF方案化疗(第一癌术后21例,第二癌术后16例)。腋淋巴结阳性超过3个者及肿瘤位于内侧者加行放疗,所有患者均口服三苯氧胺。结果25例BPBC占同期乳腺癌的1.95%(25/1280),总5年生存率为56%(14/25);同时性、异时性5年生存率分别为25%(1/4)、71.4%(15/21)。结论BPBC与单侧乳癌的生存率相近,如能早期诊断,积极进行以手术为主的综合治疗,预后较理想。Objective To explore the diagnosis ,treatment and prognosis of bilateral primary breast cancer (BPBC). Methods 25 cases of BPBC were analyzed retrospectively, including synchronic BPBC in 21 cases and heterochronic BPBC in 16 cases, all cases received ehemotherapy with CMF or CAF and oral intake of TAM, radiation was employed when there were more than 3 positive axillary lymph nodes or interlateral location of the lesions. Results 25 cases of BPBC accounted for 1.95% of all cases of breast cancer during the same period. The 5-year survival rates were 56% in general and 25% , 71.4% for synchronia and heterochronia cases.
关 键 词:乳腺肿瘤
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