暴发性肝功能衰竭预后高危因素的分析  

Analyzing the risk factors of the prognosis of fulminant hepatic failure

作　　者：叶润生[1] 

机构地区：[1]广州市花都区人民医院消化科,广东广州510800

出　　处：《河南医学研究》2005年第4期357-358,379,共3页Henan Medical Research

摘　　要：目的:探讨暴发性肝功能衰竭(fulminanthepaticfailure,FHF)预后不良的高危因素。方法:回顾了53例不同预后的FHF患者的年龄、病原学、并发症和实验室检查指标与预后的关系。结果:年龄小则预后较好。并发症与病情危险相关因素由高到低依次为:肝肾综合征>出血>感染>腹水,血清AST/ALT、TBil/DBil、TBA、Tch水平比较可见:前三项死亡组高于存活组,Tch则为存活组高于死亡组;PTA<40%、APTT>45s的患者存活率相对较低。结论:年龄、并发症情况、肝功能和凝血象指标是反映FHF患者预后的重要因素。Objective： To explore the risk factors of the bad prognosis of fulminant hepatic failure. Methods ： We analyzed the relation between prognosis and age, etiologic feature, complication, index of laboratory examination. Results ： The survival rate were more higher in the younger patients. The serum levels of AST/ALT, TBil/Dbil, TBA were significantly higher in the death group than in the survival group. The level of Tch was contrary. The survival rate was significantly higher in patients whose PTA 〉 40 %, and similar result was obtained in patients whose APTT 〈 45 seconds. Conclusion ： The age, the complication and the index of the laboratory examination are the important factors in judging the prognosis of fulminant hepatic failure.

关 键 词：暴发性肝功能衰竭 预后 高危因素 

分 类 号：R575.3[医药卫生—消化系统]