A-NK细胞对大鼠肝癌的影响  

The anti-cancer effects of A-NK cells on mice with liver cancer

作　　者：黄宏思[1] 黄卫彤[2] 覃志坚[2] 韦鹏涯[1] 黄衍强[1] 

机构地区：[1]右江民族医学院微生物学与免疫学教研室,广西百色533000 [2]右江民族医学院检验系,广西百色533000

出　　处：《右江民族医学院学报》2005年第6期788-790,共3页Journal of Youjiang Medical University for Nationalities

基　　金：右江民族医学院科研经费资助项目

摘　　要：目的探讨A-NK细胞对肝癌的抗肿瘤作用。方法分别将LAK、A-NK细胞经肝动脉注入鼠肝癌模型中,观察两组动物的生存时间。结果A-NK细胞能显著延长肝癌动物模型的生存期,与LAK细胞比较差异有高度显著性(P<0.01)。结论A-NK细胞对肝癌的抗肿瘤作用比LAK细胞强,有临床应用前景。Objective To assess the anti - cancer effects of A- NK cells on liver cancer. Methods The LAK cells and A - NK cells were injected in the hepatic artery in mouse hepatic cancer models, respectively. The survey of the mice survival time in the two groups had been done. Results A- NK cells could significantly prolong the survival time of the model mice, in comparison to the LAK cells, there was statistically significant difference （ P 〈0.01）. Conclusion A- NK cells are more effective on resistance to carcinogenesis, which is prospective in clinical use.

关 键 词：肝肿瘤 A-NK细胞 似细胞 免疫疗法 过继 大鼠锄物实验 

分 类 号：R735.7[医药卫生—肿瘤]