肝硬化腹水并发自发性细菌性腹膜炎167例临床分析  

Clinical analysis of 167 patients of hepatic cirrhosis complicated with spontaneous bacterial peritonitis

作　　者：简希尧[1] 陈艺[1] 许东发[1] 

机构地区：[1]广东省惠州市人民医院感染科,广东惠州516002

出　　处：《海南医学》2006年第1期17-18,共2页Hainan Medical Journal

摘　　要：目的探讨肝硬化腹水并发自发性细菌性腹膜炎(SBP)细菌种类以及临床特点,减少漏诊,提高患者生存率。方法对167例肝硬化腹水并发SBP患者的临床资料进行回顾性分析。结果167例肝硬化腹水并发SBP患者中69例腹水细菌培养阳性(41.32%),共分离细菌21株,包括7种细菌,以革兰氏阴性杆菌为主,大肠杆菌为主要致病菌,占43.72%;139例(83.2%)患者腹水多形核白细胞(PMN)比值≥0.50。结论肝硬化腹水并发SBP临床表现大多数不典型,腹水PMN比值是诊断SBP的可靠指标;病原菌以大肠杆菌为主,对第三代头孢菌素和第三代氟喹诺酮类药物敏感。Objective To decrease missed diagnosis and improve survival rate by investigating the bacterial categories and clinic characteristic of hepatic cirrhosis eompheated with spontaneous bacterial peritonitis （SBP）. Methods Retrospective analyze clinic information of 167 SBP eases. Results Ascites bacterial culture of 69 eases shows positive for 41.32% of total number. 21 plant bacterial separated included 7 species bacterial, almost gram negative bacilli, and colibacillus is primary pathogen for 43.72%.Polymorphonuelear （PMN） ratio of 139 eases are higher than 0.50 for 83.2% of the total number. Conclusions clinical manifestations of SBP patients are not representative, the detection of ascitie PMN is credible standard in diagnosis of SBP;Colibacillus is primary pathogen sensitive to the third generation eephalosporins and quinolones.

关 键 词：肝硬化 腹水 自发性细菌性腹膜炎 

分 类 号：R575.2[医药卫生—消化系统]