小儿葡萄状横纹肌肉瘤临床病理和影像学观察  

The Clinico-pathology and Imageology Study of Children's Botryoid Rhabdomyosarcoma:15 Cases Reports

作　　者：张美德[1] 陈峥嵘[1] 王凤华[1] 牛会林[1] 刘立炜[1] 

机构地区：[1]广州市儿童医院,广州510120

出　　处：《现代临床医学生物工程学杂志》2005年第5期420-423,共4页Journal of Modern Clinical Medical Bioengineering

摘　　要：目的研究小儿葡萄状横纹肌肉瘤的临床过程、病理形态学和影像学改变.方法对15例小儿葡萄状横纹肌肉瘤的目检、镜检和特染、免疫组化的检测以及发生在膀胱的影像学检查.结果男7例,女8例,男女之比为1∶1.14.发生部位:在膀胱9例,子宫3例,阴道3例.年龄方面,1～3岁8例,4～6岁7例,7～9岁2例,中位年龄为3岁.结论葡萄状横纹肌肉瘤为小儿较常见的中空器官的低度恶性肿瘤.早期完整切除加综合治疗预后良好,但也有复发和转移的病例.有些病例由于粘液丰富,瘤细胞稀少,瘤细胞貌似良性的未分化间叶细胞,并伴有程度不同的炎症反应,易误诊为炎症性息肉.Objective To study the clinical course, pathology and imageology of children＇s botryoid rhabdomyosarcoma. Methods 15 cases of ehildren＇s botryoid rhabdomyosarcoma were examined by maeroscopy, mierosopy, special staining and immunohistochemistry, beyond one ease situated in bladder were examined by imageology. Results 7eases were males, 8 females and the ratio of sex was 1 ： 1.14. 9 eases were located in bladder, 3 eases in uterus and 3eases in vagina. The age of 8 eases was 1 - 3 years, 7cases 4 - 6 years, 2eases 7 - 9 years, and the median age was 3 years. Conclusions Bortryoid rhabdomyosarcoma, a low potential malignaney tumor, is more ofteo seen in ehildren＇s low organs. It had good prognosis if it is eompletely reseeted and added comprehensive treatments, but it may be reeur and metastasize. Some eases are easy to misdiagnosis beeause this tumor has plentiful mueosa, inflammation and few cells that are like benign undifferential mesenchymal cells.

关 键 词：葡萄状横纹肌肉瘤 小儿 活检 影像学观察 临床病理 

分 类 号：R738.6[医药卫生—肿瘤]