ALLELE DISTRIBUTION OF FIVE X-CHROMOSOME SHORT TANDEM REPEAT LOCI IN EWENKE POPULATION OF NORTH CHINA  

作　　者：Shan-zhi Gu Teng Chen Qing-bo Liu Bing Yu Sheng-bin Li 

机构地区：[1]Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi＇an Jiaotong University, Xi＇an 710061

出　　处：《Chinese Medical Sciences Journal》2005年第4期237-241, ,共5页中国医学科学杂志（英文版）

基　　金：Supported by the National Natural Science Foundation of China(39970401).

摘　　要：Objective To study the allele genetic polymorphism of five short tandem repeat （STR） loci on X-chromosome in Ewenke population of north China and to provide basic data for forensic identification. Methods Genomic DNA was extracted from EDTA-whole blood of Ewenke population by Chelex-100. The DNA samples were amplified by PCR and were analyzed by polyacrylamide gel electrophoresis and silver staining. The sequence length variations of DXS6799, DXS8378, DXS101, HPRTB, and DXS6789 loci on X-chromosome in 98 unrelated Ewenke individuals were investigated. Results All five loci analyzed showed high polymorphism and genetic stability. The data of the five X-chromosome STR loci in Ewenke ethnic group of China was in accordance with Hardy-Weinberg equilibrium by Chi-square test. Conchusion Allele polymorphism of five X-chromosome STR loci can be used as a genetic marker for forensic identification and population genetic research.

关 键 词：allele distribution X-CHROMOSOME short tandem repeat Ewenke population 

分 类 号：R394[医药卫生—医学遗传学]