经颞浅动脉灌注氟尿嘧啶和卡铂治疗舌癌  

Arterial infusion fluorouracil and carboplatin through superficial temporal artery for tongue carcinoma

作　　者：曾东林[1] 王国华[2] 廖煜[2] 

机构地区：[1]中山大学第二附属医院口腔颌面外科,广州510120 [2]桂林医学院附属医院口腔科,桂林541001

出　　处：《口腔医学》2005年第6期351-352,共2页Stomatology

摘　　要：目的探讨术前联合应用氟尿嘧啶、卡铂诱导化疗治疗舌癌的临床效果。方法20例舌癌患者经颞浅动脉插管连续顺序灌注氟尿嘧啶和卡铂,比较化疗前、后原发肿瘤灶的大小,并记录化疗的主要不良反应。结果完全缓解(CR)18例(90%),部分缓解(PR)2例(10%),总有效率(CR+PR)100%;不良反应轻微。结论经颞浅动脉插管灌注氟尿嘧啶和卡铂是治疗舌癌的一种有效方法,不良反应发生率低且轻。Objective To investigate the clinical effects of the adjuvant chemical therapy of tongue carcinoma using fluorouracil and carboplatin. Methods Twenty eases with tongue carcinoma were treated by arterial infusion fluorouraeil and earbeplatin through the superficial temporal artery befbre surgical operation. The size of the tumor before and after treatment and the main complication of each ease after treatment were studied. Results Eighteen of the twenty（90% ） patients had a complete response to arterial infusion chemotherapy and two （ 10% ） had a partial response. The complication of chemotherapy was slight. Conclusion Arterial infusion fluorouraeil and earbeplatin through the superficial temporal artery is an effective method for the therapy of tongue carcinoma.

关 键 词：氟尿嘧啶 卡铂 颞浅动脉灌注 口腔肿瘤 化疗 

分 类 号：R739.86[医药卫生—肿瘤]