原发性颅内恶性淋巴瘤17例临床分析  

Clinical analysis of 17 cases of intracranial primary malignant lymphoma

作　　者：刘书深 孙永乐 孙学东[1] 

机构地区：[1]威海市立医院神经外科,山东威海264200 [2]威海市口腔医院口腔科,山东威海264200

出　　处：《肿瘤防治杂志》2005年第21期1658-1659,共2页China Journal of Cancer Prevention and Treatment

摘　　要：总结原发性颅内恶性淋巴瘤的临床、影像学及病理学特征。回顾性分析17例原发性颅内恶性淋巴瘤的临床资料,并对其临床、影像学及病理学检查进行分析。原发性颅内恶性淋巴瘤是颅内少见的肿瘤,临床表现复杂,颅内高压是其主要表现之一(13/17),颅脑CT和MRI检查显示肿瘤位于额颞叶多见(12/17),主要发病起源于B细胞,综合治疗效果好,总体预后差。初步研究结果提示,原发性颅内恶性淋巴瘤的临床与影像学特征缺乏特异性表现,早期诊断困难,临床误诊率高,颅内活组织病理学检查是确诊本病的主要手段,综合治疗(手术放疗和化疗)可取得较好的疗效。In order to study the clinical, radiological and pathological features of intracranial primary malignant lymphoma, the clinical, neuroradiological and pathological data of 17 intracranial primary malignant lymphoma were reviewed and analysed. Intracranial primary malignant lymphoma was uncommon intracranical tumor. It had various clinical features, and increased intracranial pressure was the main clinical feature （13/17）. Neuroradiological examinations with CT and MRI showed tumor located mainly in the frontal and temporal lobes （12/17）. The greater majority of intracranial primary malignant lymphoma was B-cell origin. Comprehensive treatment had good effect, but the prognosis of this disease was still poor. The intracranial primary malignant lymphoma patients usually did not show characteristic clincial manifestation and characteristic findings in imaging scanning. It was difficult to diagnose earlier, and misdiagnosis rate was high. Brain biopsy and pathological examination might be a reliable method to confirm malignant lymphoma. Comprehensive treatment including surgery, radiotherapy and chemotherapy could achieve better effects.

关 键 词：脑肿瘤 淋巴瘤 原发性 回顾性研究 

分 类 号：R739.4[医药卫生—肿瘤]