波利特、吗叮林与多虑平联合治疗顽固性胃食管反流病40例临床疗效观察  

Clinical Effects of Combination of Rabeprazole,Domperidone and Doxepin on 40 Patients With Refractory Gastroesophageal Reflex Disease(GERD)

作　　者：徐正富[1] 

机构地区：[1]安徽省铜陵市人民医院内科,244000

出　　处：《实用全科医学》2006年第1期47-48,共2页Applied Journal Of General Practice

摘　　要：目的探讨抗抑郁药物对治疗胃食管反流病(GERD)的疗效。方法使用波利特(雷贝拉唑钠)吗叮林与多滤平联合治疗GERD40例进行随机对照研究。结果使用多滤平的治疗组的总有效率明显高于对照组,存在显著差异(P<0.05)。结论多滤平在治疗顽固性GERD有一定的疗效,值得推广使用。Objective To observe the effects of antidepressant on GERD. Methods 80 patients with GERD were divided into 2 groups randomly： Patients in doxepin group were treated with Rabeprazole, Dompexidone and Doxepin. Patients in control group were treated with Rabeprazole Dompexidone and diazepam. Results The difference of curative effect between the two groups was significant. The total effective rate of doxepin group was higher than control group. Conclusions Doxepin is effective drug for obstinate GERD, and it＇s worth to be popularized.

关 键 词：胃食管反流病 顽固性 胃动力 精神因素 抑郁 临床疗效 

分 类 号：R573[医药卫生—消化系统] R571[医药卫生—内科学]