真核生物中mRNA结构与基因表达调控  

mRNA STRUCTURE AND GENE EXPRESSION IN EUKARYOTES Yu Changchun

作　　者：于长春[1] 王海峰[2] 

机构地区：[1]四平师范学院,四平136000 [2]山东大学,济南250100

出　　处：《松辽学刊（自然科学版）》1996年第1期32-34,共3页Songliao Journal (Natural Science Edition)

摘　　要：真核生物在翻译水平存在着多种调控机制.主要是通过控制mRNA的稳定性,对mRNA进行有选择地翻译等所实现.近年来.关于 mRNA结构在真核生物蛋白质合成过程中的调控作用屡见报道.除m^7G帽子结构.5＇UTR的长度.AUG的位置和上下文的关系外,mRNA的高级结构也是翻译调控的一个严格的参量.mRNA的结构当然也影响翻译的延伸和终止,但更重要的是影响其起始.本文就此加以综述.There are many regulation mechanisms for the translation level of eukaryotic cells, which completed mainly by the control of stability of mRNA and the selection translation of mRNA. In addition to the m'G cap structure.the length of 5'UTR and the position and context of AUG initiator codn.higher order structures within mRNA represent a critical parameter for translattion. The role of RNA in translation initiaton will be considered primarily ,athough structural elements have also been found to effect translation elongation and termination.

关 键 词：mRNA结构 翻译 调控 真核生物 基因表达 

分 类 号：Q522[生物学—生物化学]