复方四环素泼尼松膜治疗牙周炎28例  

Compound tetracyline and prednisone acetate pellicles in the treatment of 28 cases of periodontites

作　　者：李晓荣[1] 郝春玲[1] 晋溪溪[1] 

机构地区：[1]新乡市中心医院,河南新乡453000

出　　处：《新乡医学院学报》2006年第1期64-65,共2页Journal of Xinxiang Medical University

摘　　要：目的评价牙周局部应用复方四环素泼尼松膜辅助治疗牙周炎的临床效果。方法选择成人慢性牙周炎患者28例,左右侧对应牙,牙周袋深度≥4mm,且探诊出血的牙位点168个,采用随机单盲对照法,分为实验组和对照组,基础治疗后实验组牙周袋内放药,每周1次,共3次,对照组不放药。治疗后第6周、第12周时,观察菌斑指数(PLI)、牙周袋深度(PD)、探诊后出血(BOP)等指标。结果治疗后第6周和第12周时,观察组各观察指标比用药前有明显改善(P<0.01)。两次复查时,实验组改善均优于对照组,两组相比具有显著性差异(P<0.01)。结论局部应用复方四环素泼尼松膜治疗牙周炎,能够有效地改善临床症状,获得较好的临床效果。Objective To evaluate the clinical effects of compound tetracyline and prednisone acetate pellicles in the treatment of periodontites. Methods Twenty-eight adult patients with chronic periodontitis, characterized by bilateral corresponding teeth, depth of pocket was no less than 4 mm and 168 probed bleeding sites. The patients were divided randomly into observation group and control group. Routine treatment was performed in the control group. On the basis of the treatment in the control group, periodontal pocket was administered with drugs for three weeks, once a week. Indices of plaque index （PLI）, depth of pocket（PD） and bleeding on probing （BOP）, etc. were detected after 6 weeks and 12 weeks respectively, Resuits Indexes of both groups were improved obviously in the 6th week and 12th week after treatment compared with those of the two groups pre-treatment （P〈0.01）. Indexes of the observation group were better than those in the control group after twice reexamination （P〈 0.01）. Conclusion Local application of compound tetracyline and prednisone acetate pellicles in the treatment of periodontitis can effectively improve the clinical symptoms and obtain better clinical effects.

关 键 词：复方四环素泼尼松膜 局部缓释剂 牙周炎 

分 类 号：R781.4[医药卫生—口腔医学]