栀子降血糖作用的实验研究  

Experimental Studies on Fructus Gardeniae in Decreasing Blood Sugar

作　　者：黄洪林[1] 杨怀瑾[1] 刘立超[1] 邱咏薇[1] 刘杰[1] 丁舸[1] 

机构地区：[1]江西中医学院,南昌330006

出　　处：《中药新药与临床药理》2006年第1期1-3,共3页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家自然科学基金项目(29762003);江西省教育厅2003科技计划(20030504)。

摘　　要：目的研究中药栀子对正常动物及几种糖尿病模型动物血糖的影响。方法用外源性葡萄糖致高血糖、肾上腺素致高血糖、地塞米松致胰岛素抵抗和四氧嘧啶致糖尿病小鼠模型,分别观察栀子对正常和糖尿病模型小鼠血糖的影响。结果栀子能显著降低葡萄糖、肾上腺素、地塞米松和四氧嘧啶致高血糖小鼠的血糖,对正常小鼠也有一定的降糖趋势。结论中药栀子对正常小鼠和数种糖尿病模型小鼠具有降低血糖的作用。Objective To investigate the effect of decoction of Fructus Gardeniae in decreasing blood sugar level in normal mice and diabetes mellitus mice （DM）. Methods DM mice models were induced by glucose, adrenalin, desamethasone and alloxan respectively. After treatment, the influence of Fructus Gardeniae on blood sugar level in normal mice and DM mice was observed. Results Fructus Gardeniae decreased the blood sugar level significantly in DM mice and slightly in normal mice. Conclusion Fructus Gardeniae is effective in decreasing blood sugar level in both normal mice and several DM mice.

关 键 词：栀子 糖尿病 降血糖 动物模型 

分 类 号：R285.5[医药卫生—中药学]