经单鼻孔蝶窦入路显微切除垂体腺瘤  

Resecting Pituitary Adenoma by Microsurgery through Endonasal Transsphenoidal Approach

作　　者：齐洪武[1] 王政刚[1] 张旭东[1] 樊丰势[1] 张卫宁[1] 程建业[1] 王帅[1] 赵亚鹏[1] 

机构地区：[1]白求恩国际和平医院神经外科,河北石家庄050082

出　　处：《中国临床神经外科杂志》2006年第1期1-3,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的总结经单鼻孔蝶窦显微手术治疗垂体腺瘤的方法及经验。方法2002年2月至2005年3月我科运用显微外科技术,采用经单鼻孔蝶窦入路行垂体腺瘤切除术16例,其中微腺瘤3例(肿瘤直径<10mm),小腺瘤4例(10～20mm),中腺瘤7例(20～30mm),大腺瘤2例(>30mm)。结果全切除15例(93.75%,15/16)、次全切除1例(6.25%,1/16),无颅内感染、死亡病例。平均随访8个月,患者临床症状较术前均有不同程度改善,手术效果良好。结论经单鼻孔蝶窦入路是治疗垂体腺瘤的一种有效、可靠的方法,具有切除彻底、创伤小、危险小和并发症少等优点。Objective To summarize the experience in treating pituitary adenoma by microsurgery through endonasal transsphenoidal approach. Methods Sixteen patients with pituitary adenoma, of whom, 3 suffered from microdenomas （diameter〈10 mm）, 4 small adenomas （0-20 mm）, 7 middle adenomas （20-30 mm） and 2 macroadenomas （〉30 mm）, underwent pituitary adenoma resection by micrusurgery through endonasal transsphenoidal approach in our hospital from february 2002 to March 2005. Results Of 16 patients with pituitary adenoma, 15 received total resection of the tumors and 1 subtotal. No intracranial infection occurred and no patients died in all the patients. The followlng-up for mean 8 months showed that the patients were improved in the clinical symptoms and the operative effect was good. Conclusion The microsurgery through endonasal transsphenoidal approach, which is enable to complete resection with less trauma and fewer complications, is a reliable and effective method.

关 键 词：垂体腺瘤 显微手术 经鼻蝶入路 

分 类 号：R736.4[医药卫生—肿瘤] R651.13[医药卫生—临床医学]