妊娠高血压综合征性视网膜病变危险因素Logistic回归分析  

Logistic regression analysis of risk factors associated with retinopathy in pregnancy-induced hypertension patients

作　　者：李忠[1] 冼文光[1] 欧波[1] 张开颜[1] 

机构地区：[1]海南省人民医院,海南海口570102

出　　处：《中国热带医学》2006年第2期237-238,共2页China Tropical Medicine

摘　　要：目的了解妊娠高血压综合症性视网膜病变的危险因素。方法收集在产科诊断为妊娠高血压综合症产妇97例的年龄、妊娠次数、孕胡、体重、下肢水肿、尿蛋白、收缩压、舒张压、血红蛋白、红细胞压积和血型及视网膜情况,以视网膜为反应变量,其他因素为解释变量,先进行单因素非条件logistic回归分析,在此基础上选择有意义的变量(P<0.05),进行多因素非条件logistic回归分析,采用逐步筛选法(Stepwise Selection)选择变量。引入变量的显著性水平iαn=0.05,剔除变量的显著水平αoout=0.05。结果入选logistic回归模型的因素依危险程度由大至小为舒张压(OR=2.904)、尿蛋白(OR=2.481)和妊娠次数(OR=1.647)。结论控制舒张压,尿蛋白和妊娠次数有利降低视网膜病变的风险。Objective To understand the risk factors associated with retinopathy in pregnancy - induced hypertension syndrome （PHS） patients. Methods 97 PHS pregnants were examine and the data concerning the age, number of pregnancy, trimester of pregnancy, body weight, edema at lower extremities, urinary protein, systolic pressure, diastolic pressure, hemoglobin, hematocrit, blood group and retina were collected. Simple logistic regression analysis was made for analysis of all the risk factors and then those of statistically significant variables were chosen for multiple logistic regression analysis. Results The results of multiple logistic re- gression analysis showed that the statistically significant risk factors were diastolic pressure（ OR = 2. 904）, urinary protein （OR = 2. 481 ） and the number of pregnancy （ OR = 1. 647 ）. Conclusion Control of diastolic pressure, unrinary protein and number of pregnancy is effective for reducing the risk of retinopathy.

关 键 词：妊娠高血压综合症 视网膜病变 危险因素 回归分析 

分 类 号：R774.1[医药卫生—眼科]