急性脑梗死同型半胱氨酸与神经功能缺损的关系  

Relationship between plasma homocysteine and neurological impairment in patients with acute cerebral infarction

作　　者：刘高飞[1] 秦正良[1] 陈心岭[1] 

机构地区：[1]南京医科大学第三附属医院神经内科,扬州211900

出　　处：《中国实用神经疾病杂志》2006年第1期23-24,共2页Chinese Journal of Practical Nervous Diseases

基　　金：南京医科大学科技发展基金项目

摘　　要：目的探讨急性脑梗死患者血浆同型半胱氨酸(Hcy)浓度水平与神经功能缺损程度的相关性。方法采用全自动化学发光免疫分析仪测定脑梗死同型半胱氨酸的水平,神经功能缺损用中国卒中量表(GSS,1995)记分评定。结果血浆同型半胱氨酸(Hcy)的水平与脑梗死患者神经功能缺损程度两者具有相关性,Hcy水平越高,GSS评分也越高,恢复期预后越差。结论急性脑梗死时患者血浆同型半胱氨酸水平能反映病情的严重程度,且有助于评估患者的预后、指导治疗的意义。Objective To observe the relationship between change of plasma homocysteine and neurological impairment in patients with acute cerebral infarction. Methods The plasma Hcy levels were measured in patients with acute cerebral infarction by automated chemiluminescence ＇ s immune analyzer, neurological impairment was assessed by meaning of China stroke scale （ 1995 ）. Results The level of Hey has the relativity with the degree of the neurological impairment. The plasma Hey levels were higher in the patients assessed higher by meaning of scale; and the prognosis will be better in convalescence. Conclusion Plasma Hcy concentration in patients with acute stroke may reflect the severity of patients condition. It help to evaluate the prognosis of the patients and may have some significance in guiding the clinical treatment.

关 键 词：脑梗死 同型丰胱氨酸 神经功能缺损 

分 类 号：R743.32[医药卫生—神经病学与精神病学]