经皮微波热凝固疗法治疗周围型肺癌的近期疗效评价(附16例报告)  

Percutaneous microwave coagulation therapy for peripheral lung cancer: A short-term evaluation of 16 cases

作　　者：朱良明[1] 李前生[1] 蔺玉霞[1] 肖伟[1] 

机构地区：[1]济南市中心医院胸外科,济南250013

出　　处：《中国微创外科杂志》2006年第2期115-116,共2页Chinese Journal of Minimally Invasive Surgery

摘　　要：目的探讨经皮微波热凝固（percutaneous microwave coagulation therapy，PMCT）治疗周围型肺癌的临床疗效、影像学变化及不良反应。方法2003年8月～2004年10月我们在CT引导下PMCT治疗周围型肺癌16例（鳞癌9例，腺癌7例）。经皮肺穿刺将针式微波天线穿刺到肿瘤内，以2450MHz的微波、功率为65-75W每点加热3-5min，根据肿瘤大小、形状选择1点或多点加热。结果手术时间15-60min，平均35min。术后3例发生气胸，6例发生少量胸腔积液。CR1例，PR4例，NC11例。16例随访3—15个月，平均9．5个月，肿瘤转移2例，死亡1例。结论PMCT治疗周围型肺癌对不能耐良开胸手术的病人是一种有一定疗效、微刨、安全的新方法。Objective To evaluate the clinical effects, CT features and side-effects of percutaneous microwave coagulation therapy （PMCT） in the treatment of peripheral lung cancer. Methods CT-guided PMCT was applied to 16 cases of peripheral lung cancer from August 2003 to October 2004 in this hospital. Pathological or cytological findings showed 9 cases of squamous carcinoma and 7 cases of adenocarcinoma. A needle microwave antenna was applied into the tumor percutaneously under CT guidance. In each emission of microwave, the tumor was ablated with a 2 450 Hz microwave coagulation output of 65 - 75 W for 3 - 5 min. According to the size and shape of the tumor, single or multiple ablation emission was selected. Results The operation time was 15 -60min （ mean, 35 rain）. Complete remission （CR） was achieved in 1 case, partial remission （PR） in 4 cases, and no changes （NC） in 11. Follow-up observations in the 16 cases for 3 - 15 months （mean, 9.5 months） found 2 cases of tumor metastasis and 1 case of death. Conclusions Percutaneous microwave coagulation therapy is a safe, micro-invasive, and effective treatment for the management of peripheral lung cancer.

关 键 词：肺肿瘤 经皮微波热凝固 

分 类 号：R734.2[医药卫生—肿瘤]