N,N′-二苯基丙二酰胺的合成  

Preparation of N,N′-Diphenylmalonamide

作　　者：王莉贤[1] 郭强[1] 潘安健[2] 

机构地区：[1]上海大学材料学院,上海200436 [2]上海应用技术学院化学工程系,上海200235

出　　处：《化学世界》2006年第2期102-104,共3页Chemical World

基　　金：上海高等学校科学技术发展基金项目(03KH11);上海市重点学科建设基金项目(P1502)

摘　　要：以二甲苯为溶剂,丙二酸二乙酯和苯胺为原料,在物料比为n(丙二酸二乙酯)∶n(苯胺)=1∶2.2的条件下,采用边反应边将乙醇蒸出的方法,回流反应4 h,得到N,N′-二苯基丙二酰胺粗产物,用异丙醇作溶剂,以自行设计改进的缩合双套管分离装置为提取器,将粗产物中的杂质萃取,获得N,N′-二苯基丙二酰胺的质量分数大于98%,收率可达92%。通过熔点I、R谱及元素的测定对产物进行了表征。N, N＇-Diphenylmalonamide with a purity of 98 % was prepared by reaction of malonic ester and aniline with a molecular ratio of 1 ： 2.2 in xylene. Ethanal was distilled out from the reaction mixture during reaction, and then the mixture was refluxed for 4 h. The extraction was carried out by using isopropanol as extractant and a twin-tube separation instrument designed and made by ourself. The target compound was confirmed by melting poin test, IR spectroscopy and elemental analysis. The yield was 92 % .

关 键 词：丙二酸二乙酯 苯胺 N N’-二苯基丙二酰胺 异丙醇 提取 

分 类 号：TQ225[化学工程—有机化工]