子宫动脉药物灌注和栓塞治疗胎盘部位滋养细胞瘤  

Uterine artery drug pouring and embolism treatment for placental site trophoblastic tumor

作　　者：杨丹[1] 苏璇[2] 韩立敏[1] 李欣[1] 

机构地区：[1]复旦大学附属中山医院妇产科,上海200032 [2]淮南新华医院妇产科,安徽淮南232052

出　　处：《复旦学报（医学版）》2006年第1期78-80,共3页Fudan University Journal of Medical Sciences

摘　　要：目的探讨治疗胎盘部位滋养细胞瘤(PSTT)新的有效方法。方法报道2例PSTT病例的诊治过程,其中1例子宫增大如妊娠4个月,伴不规则子宫流血。采用子宫动脉灌注甲氨蝶呤(MTX)200mg,子宫动脉栓塞。结果治疗后1周内子宫病灶缩小,血-βhCG下降,第2个月月经恢复正常,其中1例已随访3年余。结论彩超和核磁共振有助于诊断,诊刮有助鉴别诊断。子宫动脉MTX灌注及子宫动脉栓塞治疗效果显著,不良反应极少,有条件者可作为治疗PSTT之首选。Purpose To explore a new and effectual management of the placental site trophblastic tumor （PSTT）. Methods Two patients with PSTT undergone interventional radiology management. One of them had an uterus as large as 4 months pregnancy and with abnormal uterine bleeding. Metholrexate （MTX） was poured into uterine arterine and uterine artery embolism （UAE）. Results After one-week treatment, the uterine focus was reduced and serum β-human chorionic gonadotropin （HCG） level was declined. Menstruation was back to normal in the secondary month. Conclusions Color-ultrasound and magnetic resonance imaging （MRI） provided useful information for PSTT diagnostics, and curattege could provide additional distinction information. The method of pouring MTX into the uterine arteries and UAE treatment is an effectual and harmless remedy for PSTT.

关 键 词：胎盘部位滋养细胞肿瘤 子宫动脉栓塞 灌注 

分 类 号：R737.33[医药卫生—肿瘤] R815[医药卫生—临床医学]