尼莫通输液治疗缺血性脑梗塞的临床观察  

Clinical Observation of Intravenous Nimotop Therapy in Cerebral Ischemic Infarction

作　　者：于沁[1] 沈鸣九[1] 

机构地区：[1]南京医科大学第一附属医院神经内科

出　　处：《南京医科大学学报（自然科学版）》1996年第6期543-544,共2页Journal of Nanjing Medical University(Natural Sciences)

摘　　要：应用钙离子拮抗剂尼莫通输液治疗缺血性脑梗塞３２例与中药脉络宁治疗４５例进行对照，前者总有效率９６．９％，后者８８．９％，Ｐ＞０．０５，二者对脑梗塞均有良好疗效；显效率分别为８１．３％和６０．０％，Ｐ＜０．０５，提示尼莫通对神经功能缺损的恢复疗效更显著。尼莫通对病程处于早期的轻、重症患者及有智能障碍者疗效明显，而脉络宁作用缓和而持久，故对脑梗塞患者早期先予尼莫通。The effect of intravenous Nimotop, a calcium channel antagonist, in the treatment of cerebral infarction in 32 patients was compared with that of 45 control patients treated with traditional Chinese medicine Mailuoning. The total effective rate in the former was 96.9% while in the latter it was 88.9%( P >0.05). Both had a good effect on patients with cerebral infarction. The effectual rates of the two groups were 81.3% and 60.0%( P <0.05), respectively. Nimotop had a more significant effect on the recovery of neurdogical deficits and a better effect on the patients in the early stage of the disease and/or with mental impairment. The effect of Mailuoning was moderate and sustaining. So it was appropriate to treat patients with cerebral infarction with Nimotop in the early stage of the disease and then followed by Mailuoning for further therapy.

关 键 词：尼莫通 脉络宁 缺血性脑梗塞 

分 类 号：R743.330.5[医药卫生—神经病学与精神病学] R969.4[医药卫生—临床医学]