Apium graveolens L. accelerating differentiation of neural stem cells in vitro  

作　　者：文铁桥 陆伟 陈付学 宋红生 赵翠萍 余涛 

机构地区：[1]Laboratory of Neural Molecular Biology, School of Life Sciences, Shanghai University, Shanghai 200444, P.R.China

出　　处：《Journal of Shanghai University(English Edition)》2006年第1期89-94,共6页上海大学学报（英文版）

基　　金：ProjectsupportedbyNationalBasicResearchProgramofChina(GrantNo.2006CB500702),NationalNaturalScienceFounda-tionofChina(GrantNo.30570590),ShanghaiMunicipalCommis-sionofScienceandTechnologyBasicResearchFunds(GrantNos.03JC14030,03JC14061),andScientificResearchFounda-tionfortheReturnedOverseasChineseScholarsofStateEduca-tionMinistry(GrantNo.JWSL2003406)

摘　　要：To evaluate the action of Apium graveolens L. on the growth and differentiation of neural stem cells （NSCs）, cells culture and animal experiment were performed. NSCs were isolated from the striatum of SD rat embryo were cultured in the medium containing aqueous extract from Apium graveolens L（AAG）.and/or the serum derived from mice treated with Apium graveolens L （SAG）. The results show that AAG promoted the survival and growth of NSCs in low concentration. Apium graveolens L. leaves aqueous extract promoted the proliferation of NSCs in relatively high concentration. SAG significantly accelerated the differentiation of NSCs.To evaluate the action of Apium graveolens L. on the growth and differentiation of neural stem cells （NSCs）, cells culture and animal experiment were performed. NSCs were isolated from the striatum of SD rat embryo were cultured in the medium containing aqueous extract from Apium graveolens L（AAG）.and/or the serum derived from mice treated with Apium graveolens L （SAG）. The results show that AAG promoted the survival and growth of NSCs in low concentration. Apium graveolens L. leaves aqueous extract promoted the proliferation of NSCs in relatively high concentration. SAG significantly accelerated the differentiation of NSCs.

关 键 词：neural stem cells Apium graveolens L. DIFFERENTIATION proliferation. 

分 类 号：Q254[生物学—细胞生物学]