骨移植牙种植体一期植入Ⅻ型胶原mRNA表达的研究  

Type Ⅻ Collagen mRNA Expression in Bone Graft with Simultaneous Insertion of Dental Implants

作　　者：谢春 武斌 刘流[2] 秦霞南[2] 温玉明[3] 李龙江[3] 

机构地区：[1]深圳市龙华人民医院口腔科,深圳518109 [2]昆明医学院第一附属医院口腔颌面外科,昆明650032 [3]四川大学华西口腔医学院,成都610041

出　　处：《昆明医学院学报》2006年第1期46-49,共4页Journal of Kunming Medical College

基　　金：云南省应用基础研究基资助项目(97CO29Q)

摘　　要：目的研究不同类型骨移植牙种植体复合同期植入后种植体周围膜的形成特点.方法采用恒河猴10只随机分配,进行自体髂骨腓骨移植,同期植入种植体,切取标本后进行Ⅻ型胶原mRNA的原位杂交.结果Ⅻ型胶原mRNA对照组一段式种植体标本中8、16周均有表达.结论Ⅻ型胶原表达对其结构选择很重要,并且在时间上也有选择,它可能与维持成熟牙周膜承受咀嚼压力有关.Objective To investigate insertion of dental implant. Methods Ten Each group was performed vascularized bone type Ⅻ collagen mRNA expression in bone graft with simultaneous experimental monkeys were randomly divided into three groups. graft （ VBG）, non - Vasculariaed bone graft （NVBG） with simultaneous insertion of a titanium dental implant. The harvested tissue specimens were analysed in situ hybrization for collagen Ⅻ. Results In the control group, Ⅻ collagen mRNA was expressed after the dental implants were inserted eight and sixteen weeks. Conclusions The expression of collagen Ⅻ mRNA is determined by spatial structure and temporal choice. It may be related to the function of periodontal ligament.

关 键 词：骨移植 牙种植体 Ⅻ型胶原 原位杂交 

分 类 号：R782[医药卫生—口腔医学]