脑脓肿扩散加权成像与多体素氢质子波谱研究  

Role of Diffusion Weighted Imaging （DWI） and ^1 H-MRS in the Diagnosis of Brain Abscess

作　　者：李宗芳[1] 田伟[1] 顾青[1] 徐江波[1] 孙春涛[1] 周泽俊[1] 

机构地区：[1]昆明医学院第一附属医院磁共振室,昆明650032

出　　处：《放射学实践》2006年第1期9-12,共4页Radiologic Practice

基　　金：云南省教育厅科学研究基金项目(02QY138)

摘　　要：目的:探讨磁共振扩散加权威像(DWI)与磁共振氢质子波谱成像(1H-MRS)技术联合应用对脑脓肿的诊断价值。方法:对11例脑脓肿患者行DWI(SE-EPI序列)和多体素点分辨波谱分析法(PRESS-SI序列)MRS检查,并使用随机分析软件包Functool 2进行图像分析和处理,获得病灶的表观扩散系数(ADC)图和波谱图,比较DWI和MRS对脑脓肿的诊断价值。结果:9例脑脓肿于DWI上呈高信号,2例为混杂信号。MRS上10例检测到氨基酸(AA)峰,其中2例脓液培养见厌氧菌生长者波谱图上可见乙酸(Ac)峰和琥珀酸(Suc)峰。结论:应联合应用DWI和1H-MRS对脑脓肿进行诊断和鉴别诊断。Objective.. To investigate the value of diffusion weighted imaging （DWI） and ^1 H MRS in the diagnosis of brain abscess. Methods..ll patients with brain abscess had DWI and ^1 H MRS using 1.5T MR scanner were retrospectively analyzed. DWI was performed using SE EPI sequence and PRESS-SI sequence was used for ^1 H MRS. Apparent diffusion coefficient （ADC） values and metabolite patterns observed at ^1 H MRS were obtained by Functool 2. The efficacy of these modalities in the diagnosis of brain abscess were compared. Results. Hyper intensity was shown in the lesions of the 9 patients with DWl,the other 2 patients had heterogeneous hypo or hyper intensity. AA were observed in 10 patients on ^1 H-MRS,Ac and Suc were observed in 2 patients with positive culture for obligate aerobes. Conclusion.. Not all brain abscess lesions showed hyper intensity on DWI,demonstration of hyper intensity with reduced ADC is not specific for brain abscess. On ^1 H-MRS,AA were specific for the diagnosis of brain abscess,but not all brain abscess leisions showing AA. DWI combined with ^1 H MRS is recommended for the diagnosis and differential diagnosis for patients with suspected brain abscess.

关 键 词：磁共振波谱学 扩散加权成像 脑脓肿 

分 类 号：R742.7[医药卫生—神经病学与精神病学]