糖尿病性脑梗塞与非糖尿病性脑梗塞表现及预后比较  

Comparison of manifestation and prognosis in cerebral infarction patients with or without diabetes mellitus

作　　者：廉晓宇[1] 李晓飞[1] 杨军[1] 王浩岩[1] 宣兆博[1] 

机构地区：[1]黑龙江佳木斯大学第一附属医院神经外科,154002

出　　处：《中华神经医学杂志》2006年第1期70-72,共3页Chinese Journal of Neuromedicine

摘　　要：目的探讨糖尿病性脑梗塞与非糖尿病性脑梗塞患者病因及预后。方法选取102例非糖尿病性脑梗塞为非糖尿病组,74例糖尿病性脑梗塞为糖尿病组,两组均给予常规治疗措施,包括降血糖基础治疗、血管扩张药治疗、高压氧、神经营养、脑细胞活化剂、20%甘露醇脱水,24例进行静脉溶栓,余给予对症处理。结果两组脑梗塞患者在高血压(P<0.01)、肢体偏瘫(P<0.05)、基底节区梗塞(P<0.01)、血脂异常(P<0.05)、重残率(P<0.01)、治愈率(P<0.05)等方面相比均有显著的统计学意义。结论糖尿病性脑梗塞组的疗效及预后明显较非糖尿病性脑梗塞组差。其不良预后与高血糖有关,且糖尿病导致高血压、高血脂症、心脏改变和脑心综合征。Objective To study the pathogeny and prognosis in diabetes mellitus patients of cerebral infarction and nondiabetes mellitus patients of cerebral infarction. Methods 102 cases of nondiabetes mellitus of cerebral infarction were chosen as nondiabetes group; 74 cases of diabetes mellitus of cerebral infarction as diabetes group, General treatment was given such as： basic treatment of diabetes mellitus, angiectatic druggery, hybaroxia, neurotrophic medication, neuroprotective drugs, neuractivator and 20%mannite in the two group. 24 cases fibrinolytic therapy in vein. Other patients were managed normally. Results There was significantly difference between hypertension（P〈0.01）, hemiplegia（P〈0.05）, putaminal infarction （P〈0.01）, hyperlipemia（P〈0.05）, deformity rate（P〈0.01） and cure rate（P〈0.05） in the two groups. Conclusion The curative effect and prognosis in diabetes group were significantly lower than that in nondiabetes group. Hyperglycemia was important factor in the prognosis and diabetes mellitus caused hypertension, hyperlipoproteinemia, hypertensive cardiopathy and cerebrocardiac syndrome.

关 键 词：糖尿病 脑梗塞 预后 

分 类 号：R743.33[医药卫生—神经病学与精神病学]