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作 者:裘松波[1] 谭颍徽[1] 张纲[1] 王建华[1] 李忠禹[1]
机构地区:[1]第三军医大学附属新桥医院口腔科,重庆400037
出 处:《临床口腔医学杂志》2006年第1期31-32,共2页Journal of Clinical Stomatology
摘 要:目的:总结头颈部横纹肌肉瘤(RMS)的治疗经验,探讨影响其预后的相关因素。方法:分析20年间诊治的31例RMS的临床资料,对其年龄、性别、肿瘤原发部位、诊断、临床分期、治疗方法及效果进行统计分析。结果:RMS 3年、5年生存率分别为51.6%、41.9%;Ⅰ期、Ⅱ期5年生存率为52.6%,Ⅲ期5年生存率为37.5%。手术后20%病人发生远处转移,16%颈淋巴结转移,36%局部复发。结论:RMS恶性程度高,预后与临床分期及治疗方法有关,早期诊断及采用手术+放疗+联合化疗的综合治疗是提高疗效的重要途径。Objective: The purpose of this study was to review the treatment of the results and investigate the related prognosis factors of head and neck rhabdomyosarcma. Method: Medical records of 31 cases of head and neck rhabdomyosarcoma in our hospital during the past twenty years were analyzed. Then, demographic information regarding age, gender, primary tumor site, diagnosis, clinical stage , treatment and survival rate at diagnosis were obtained on this patients. Result: A follow up of all the patients but three cases showed a 3 year survival rate of 51.6%, 5 year survival rate of 41.9%. The survival rate of 5 Years are 52.6% for clinical stage Ⅰ , Ⅱ and 37.5% for clinical stage Ⅲ. After surgery , 20% of the patients had distant metastasis , 16% of the patients had lymph node metastasis and the local recurrent rate was 36 %. Conclusion: Rhabdomyosarcoma of the head and neck is a highly malignant tumor, prognosis is related to the clinical stage and method of treatment. Early diagnosis and proper wide excision of tumor combined with radiotherapy and chemotherapy are important in imoroving the theraoeutic results.
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