内镜超声引导下腹腔神经丛阻滞术治疗胰腺癌痛  

Endoscopic ultrasound guided celiac plexus neurolysis for pancreatic carcinoma pain.

作　　者：叶丽萍[1] 邓燕勇[1] 毛鑫礼[1] 林敏华[1] 

机构地区：[1]浙江省台州医院消化二科,临海317000

出　　处：《胰腺病学》2006年第1期23-26,共4页Chinese JOurnal of Pancreatology

摘　　要：目的探讨内镜超声(EUS)引导下腹腔神经丛注射无水酒精对胰腺癌痛的治疗作用。方法对3例胰腺癌病例记录疼痛分数并随访,用纵轴式彩色EUS显示腹主动脉第一分支,在其两侧注射无水酒精。结果3例胰腺癌患者均有肿瘤转移征象。注射前疼痛分数VAS为:8.0±1.0,治疗后疼痛明显缓解或消失。1例注射后发生体位性低血压,1例出现腹泻。全部病例无感染及穿孔发生。结论EUS引导下腹腔神经丛阻滞术能够安全有效地缓解胰腺癌痛。Objective To evaluate safety and effectiveness of endoscopic ultrasound guided celiac plexus neurolysis （ELIS-CPN） for analgesia of pancreatic carcinoma pain. Methods Included in this study were 3 patients with pancreatic carcinoma. Using a linear array endoscopic ultrasonagraphy and a needle catheter, transgastric injection of the celiac plexus with bupivacaine and 98% dehydrated absolute alcohol was performed. The visual analogue scale （VAS） was recorded before and after ELIS- CPN. Results VAS for pancreatic carcinoma was 8.0 ± 1.0 before CPN, and obviously decreased or disappeared after EUS-CPN treatment. Complications included orthostatic hypertension in 1 patient, and diarrhea in 1 patient. There was no infection or perforation. Conclusions EUS-CPN is a safe and effective means of relieving pancreatic carcinoma pain.

关 键 词：内镜超声 腹腔神经丛 胰腺肿瘤 疼痛 酒精 治疗应用 

分 类 号：R735.9[医药卫生—肿瘤]