贲门腺癌P170蛋白表达的研究  

Study on P170 Protein Expression in Cardiac Adenocarc Inoma

作　　者：彭学宏[1] 陈暖[1] 许建衡[1] 林静华[1] 焦晓阳[1] 

机构地区：[1]汕头大学医学院第一附属医院,广东汕头515041

出　　处：《实用医技杂志》2006年第2期188-189,共2页Journal of Practical Medical Techniques

摘　　要：目的:研究并探讨P170蛋白在贲门腺癌组织中的表达及其意义。方法:用流式细胞术检测55例贲门腺癌患者癌组织和距离肿瘤5 cm以上癌旁正常组织P170。结果:55例贲门腺癌组织P170阳性表达率为50.9%,癌旁正常组织未见P170表达,两者差别有统计意义。结论:贲门腺癌组织中具有多药耐药性,检测癌组织P170表达水平对化疗效果有一定意义。Objective To study the expression and signieance of P170 protein in cardiac adenocareinoma. Methods The expression of P170 protein in 55 cases of cardiac adenocarcinoma was detected by flow cytometry. Results The positive expression rate of P170 protein was 50.9% in 55 cases of cardiac cancer tissue. Normaltissue near cancer has no positive expression of P170 protein. There was an obvious difference between normal and cancer tissue. Conclusion There was multiple drug tolerlance in cardiac adenocarcinoma,detection of P170 protein expression in cancer tissue had significance in evaluation of chemotherapy.

关 键 词：贲门肿瘤 药物耐受性 基因表达 流动血细胞计数 

分 类 号：R735.2[医药卫生—肿瘤]