电化学治疗颌面、口腔肿瘤的疗效分析  

Analysis of Clinical Effect of Electrochemical Therapy on Tumors of Maxillofacial-Oral Cavity

作　　者：李京宏[1] 辛育龄[1] 张伟[1] 

机构地区：[1]卫生部中日友好医院,100029

出　　处：《实用癌症杂志》2005年第6期627-629,共3页The Practical Journal of Cancer

摘　　要：目的探讨电化学治疗颌面、口腔肿瘤的临床效果.方法应用我国研制的ZAY-B型电化学治疗仪和特制的铂金电极针治疗161例颌面、口腔肿瘤患者,根据病变部位和肿瘤体积选择麻醉方法.经过套管针将治疗电极直接插入瘤体,保护瘤体周围的正常组织,将电极连接至电化学治疗仪开始治疗.治疗电压6～8 V,电流保持在60～100 mA,电量按肿瘤直径每1 cm给80～100 C.结果161例中CR 71例(44.1%),PR 56例(34.8%),NC 23例(14.3%),PD11例(6.8%),CR+PR为78.9%(127/161).随访1、3、5年生存率分别为92.5%(149/161)、63.4%(102/161)和36.0%(58/161).结论电化学疗法简便易行,安全有效,创伤小,恢复快,对容貌及器官功能影响小,是治疗颌面、口腔肿瘤的1种全新方法.Objective To investigate the clinical effect of electrochemical therapy on tumors of maxillofacial-oral cavity. Methods The electrochemical therapy instrument of model ZAY-B and the electrodes made of platinum were used for the treatment of 161 patients suffered from tumors of maxillofacial-oral cavity, the anaesthetic methods were determined according to the position and shape of the tumors. Electrodes were inserted into the tumor through a trocar directly. Normal tissuewas protected by the spaghetti and the electrodes were connected to electrochemical therapy device, than the treatment began. The therapeutic voltage was 6-8 V, electric current 60-100 mA. The quantity of electricity was 80-100 Coulombs per 1.0 cm diameter of the tumor. Results 71 cases（44.1% ）were CR in 161 eases of tumors of maxillofacial-oral cavity,56 eases（34.8%）were PR,23 cases（14.3% ）were NC, 11 cases（＆ 8% ）were PD. The rate of CR ＋ PR were 78.9 %. 1,3,5 years survival rate of our group were 92.5% （149/161） ,63.4% （102/161） and 36.0 % （58/161） respectively. Conclusion Electrochemical therapy is easy to handle,safe and efficacy,less traumatic,with a quick recovery and has a little impact on patients features. It is totally a new method for treating the tumors of maxillofacial-oral cavity.

关 键 词：电化学疗法 颌面口腔肿瘤 临床疗效 

分 类 号：R739.8[医药卫生—肿瘤]