硼酸化合物与β-环糊精及其衍生物包合作用的研究  

Study on the Inclusion Interaction of 4′-Dipenylamino-4-(1,1′-biphenyl) Boronic Acid with β-Cyclodextrin and Its Derivatives

作　　者：王仲如[1] 双少敏[1] 李仲辉[2] WONG Man-shing 

机构地区：[1]山西大学化学化工学院,山西太原030006 [2]香港浸会大学化学系,香港

出　　处：《山西大学学报（自然科学版）》2006年第1期60-64,共5页Journal of Shanxi University(Natural Science Edition)

基　　金：国家自然科学基金(20275022)

摘　　要：采用荧光光谱法研究了新合成具有分子内电荷转移性质的硼酸化合物:对-二苯氨基联二苯基硼酸(DBBA)与β-环糊精(-βCD)、羧甲基-β-环糊精(CM--βCD)、磺丁醚-β-环糊精(SBE--βCD)的包合行为,且测定了其包合物的包合常数,结果表明:在DBBA溶液中加入β-环糊精及其衍生物时,其荧光光谱发生蓝移、荧光强度增加,环糊精对DBBA的包合能力的大小为SBE--βCD>CM--βCD>-βCD.同时,采用分子力学计算和计算机模拟技术预测了DBBA与-βCD形成包合物的最优化构型.The inclusion behavior of P- （diphenylamino）-biphenyl boronic acid （DBBA） with β-Cyclodextrin （ β-CD ）, carboxymethyl- β-Cyclodextrin （CM-β-CD） and sulfobty-β-Cyclodextrin （ SBE-β-CD ） was investigated by using steady-state fluorescence. We observed that the emission was slightly blue shifted and the fluorescence intensity of the DBBA increased as the concentration of β-CD was increased. The formation constants of inclusion complexes were obtained and the result suggested that the complex preferred 1 ： 1 （DBBA： CD）stoichiometry and the molecular inclusion ability is SBE-β-CD〉 CM-β-CD 〉 β-CD. Furthermore ,the spatial configuration of the complex has been proposed based on molecular modeling.

关 键 词：Β-环糊精 对-二笨氨基联二苯基硼酸 稳态荧光 分子内电荷转移 

分 类 号：O657.3[理学—分析化学]