Characterization of the neutralizing activity of three anti-human TNF monoclonal antibodies and prediction of their TNF epitopes by molecular modeling and mutant protein approach  

作　　者：Cansheng Zhu Xuesong Liu Jiannan Feng Wei Zhang Beifen Shen Weiming Ou＇yang Yunxin Cao Boquan Jin 

机构地区：[1]Department of Immunology, Fourth Military Medical University, 17 West Changle Road, Xi＇an, Shaanxi 710032, PR China [2]Department of Molecular Immunology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, P.O. Box 130 （3）, Beijing 100850, PR China

出　　处：《中国生物学文摘》2006年第1期52-52,共1页Chinese Biological Abstracts

关 键 词：瘤坏死因子 单克隆抗体 压制活性 TNF表位 分子图形 突变型蛋白质 

分 类 号：R73-3[医药卫生—肿瘤]