B超引导腹腔神经节毁损治疗胰腺癌疼痛  

Evaluation of Analgesia on Pancreatic Carcinoma with Celiac Ganglion Denervation by B-us Guidance

作　　者：汪涛[1] 田伏州[1] 蔡忠红[1] 汤礼军[1] 陈涛[1] 石力[1] 陈琪[1] 

机构地区：[1]成都军区总医院全军普外中心,610083

出　　处：《中华临床医学卫生杂志》2006年第1期12-13,共2页China Journal of Clinical Medicine Hygiene

摘　　要：目的评价超声介导腹腔神经节去除在胰腺癌疼痛中的治疗地位。方法采用B超定位，实时超声动态监测经皮穿刺，于腹腔动脉干根部旁侧注入无水乙醇15ml，对97例胰腺癌痛患者实施腹腔神经节去除术。比较治疗前后疼痛的视觉模拟评分（VAS）以及血清SP水平变化。结果97例中仅1例穿刺失败，成功率98．7％，无急性胰腺炎、腆瘘及出出等穿刺并发症；VAS及SP较术前明显降低（P〈0.01，P〈0．05）治疗总有效率87．5％，显效率76．1％，12例无效。结论超声介导腹腔神经节去除术安全可靠，能显著减轻胰腺癌疼痛。Objective To evaluate the analgesic therapy of celiac ganglion denervation guided by B-us on patients of pancreatic carcinoma with intractable pain. Methods 97 cases with advanced pancreatic carcinoma accepted chemical denervation 15ml pure alcohol injection around celiac ganglion by ultrasound guidance. The varieties of VAS and serum SP level were compared between pre-therapy and post-therapy. Results Successful rate of puncture was 98.7%, with 1 loss. No serious complications such as acute pancreatitis, pancreatic fistula, bleeding or celiac infection in our study. VAS and serum SP level significantly decreased after treatment（P 〈 0.01, P 〈 0.05）, with total effective rate 87.5%, remarkable effective rate 76.1%, 12 cases without effect. Conclusion We suggest that celiac ganglion denervation by ultrasound guidance proves to be highly safe, and can evidently relieve pain and improve the living quality on patients with advanced pancreatic carcinoma.

关 键 词：胰腺癌 疼痛治疗 腹腔神经节去除术 超声介导 

分 类 号：R735.9[医药卫生—肿瘤]