重症急性胰腺炎患者胰腺感染的相关因素分析及防治措施  

Relative factors and preventive measures of pancreatic infection in severe acute pancreatitis.

作　　者：乔世峰[1] 孙家邦[1] 李非[1] 

机构地区：[1]首都医科大学宣武医院普外科,北京北京世纪坛医院普外科100053

出　　处：《中国综合临床》2006年第3期252-253,共2页Clinical Medicine of China

摘　　要：目的探讨重症急性胰腺炎(SAP)患者胰腺感染发生的相关因素及其预防措施。方法对246例SAP患者的性别、病因、Ranson评分、APACHEⅡ评分、低氧血症、腹腔室隔综合征、肾功能衰竭、血淀粉酶水平、尿淀粉酶水平、手术与否、禁食天数、是否应用呼吸机及生长抑素等因素进行多因素分析。结果246例SAP患者中30例(12.2%)发生胰腺感染。胰腺感染组禁食时间明显多于无胰腺感染组(P<0.01)。低氧血症、肾功能衰竭、手术与否以及是否应用有创呼吸机在两组之间比较差异有显著性(P<0.05或0.01)。结论在SAP发病过程中,禁食时间较长、低氧血症、肾功能衰竭、手术以及应用有创呼吸机可能是导致胰腺感染发生的重要因素。Objective To study the related factors and the preventive measures of pancreatic infection in severe acute pancreatitis （SAP）. Methods The clinical and laboratory data including sex, pathogenesis, Ranson score, APACHE Ⅱ score, hypoxemia, abdominal compartment syndrome, renal dysfunction, serum amylase level, urine amylase level, operation, fasting time, somatostatin were analyzed by multiple analysis in 246 cases of SAP. Results 30 of 246（ 12.2% ） SAP patients developed pancreatic infection. The fasting time in pancreatic infection group was significantly longer than that of non-pancreatic infection group （ P 〈 0.01 ）. There was significant difference in hypoxemia,renal dysfunction, operation and using of respirator between groups （ P 〈 0.05 or P 〈 0.01 ）. Conclusion Fasting time, hypoxemia, renal dysfunction, operation and using of respirator may be the important factors in pancreatic infection.

关 键 词：胰腺炎 感染 

分 类 号：R576[医药卫生—消化系统]