奥美拉唑、羟氨苄青霉素、甲硝唑治疗消化性溃疡疗效观察  

Effect of Omeprazole,Amoxicillin and Metronidazole on Peptic ulcer

作　　者：史沛荣 王翠霞[2] 尉伟[1] 董丽丽[1] 

机构地区：[1]青岛市市南区人民医院,山东青岛266002 [2]青岛市第八人民医院,山东青岛266100

出　　处：《实用临床医学（江西）》2006年第2期11-12,共2页Practical Clinical Medicine

摘　　要：目的:观察奥美拉唑、羟氨苄青霉素、甲硝唑三联疗法对消化性溃疡的疗效。方法:将42例消化性溃疡患者随机分为两组:观察组22例,奥美拉唑20 mg,口服,1次/d,羟氨苄青霉素1 000 mg,口服,2次/d,甲硝唑400 mg,口服,2次/d,1周为1个疗程。对照组20例,雷尼替丁150 mg,口服,2次/d,4周为1个疗程。治疗4周后复查胃镜。结果:两组消化性溃疡的愈合率分别为91%和60%,有显著性差异(P<0.05)。观察组仅出现口干2例,恶心1例。结论:奥美拉唑、羟氨苄青霉素、甲硝唑治疗消化性溃病疗效好,不良反应少。Objective：To observe the effects of Omeprazole, Amoxicillin and Metronidazole on pep- tic ulcers. Methods. Forty-two patients with dunodenal or gastric ulcer were divided into two groups randomly. The first group （22 cases） received Omeprazole 20mg po, qd for 1 week and Amaoxicillin 1 000 mg po, bid for 1 week and Metronidaole 400mg po, bid for 1 week. The second group received Ranitidine 150 mg po,bid for 4 weeks. All patients had repeated endoscopy after 4 weeks of treatment：Results. The ulcer healing rates of the first and second groups were 91% and 60%, respectively. Conclusion： The peptic ulcer healing rate of the first group was higher than that of the second group with a significant difference between the two groups（P〈（ 0. 05）.

关 键 词：消化性溃疡 奥美拉唑 羟氨苄青霉素 甲硝唑 雷尼替丁 

分 类 号：R573[医药卫生—消化系统]