金栀含漱液用于感染根管冲洗消毒的细菌学观察  

Antibacterial effect of Jinzhi Hanshuye on infected root canals

作　　者：刘长虹[1] 尹仕海[2] 陈蕾[1] 

机构地区：[1]广东省口腔医院.南方医科大学附属口腔医院,广东广州510280 [2]四川大学华西口腔医学院牙体牙髓科,四川成都610041

出　　处：《上海口腔医学》2006年第1期15-18,共4页Shanghai Journal of Stomatology

摘　　要：目的:观察金栀含漱液对感染根管冲洗消毒的抗菌效果。方法:选择27例患者的感染根管患牙30颗,随机分为实验组和对照组,每组15颗。实验组采用金栀2倍稀释液冲洗根管,浓缩液作为根管消毒药物。对照组采用氯亚明冲洗根管,氢氧化钙药尖消毒根管。根管预备冲洗前、预备冲洗后、封药后分别取细菌样本进行厌氧培养、分离和鉴定,计算并采用重复测量的方差分析比较2组细菌检出率、CFU随时间的变化趋势。结果:实验组专性厌氧菌的检出率由73.3%下降到预备冲洗后的46.7%和封药后的13.3%,对照组厌氧菌的检出率由73.3%下降到预备冲洗后的20.0%和封药后的26.7%,2组细菌检出率无统计学差异(P=0.9721)。实验组专性厌氧菌CFU由1462.9下降为预备冲洗后的27.9和封药后的15.7,对照组厌氧菌CFU由1402.8下降到预备冲洗后的14.0和封药后的45.1,2组细菌检出量无统计学差异(P=0.688)。结论:金栀含漱液对感染根管内厌氧菌有良好的抗菌效果。PURPOSE： To evaluate antibacterial effects of Jinzhi Hanshuye on infected root canals. METHODS： 30 infected single-root-canals were collected from 27 clinical patients, and randomly divided into two groups. In the experimental group, Jinzhi Hanshuye was used as irrigating solution and intracanal medicament, while in the control group tosylchloramide sodium irrigating and calcium hydroxide disinfecting root canals were adopted. Microbiological sampling was performed before treatment, after instrumentation, and after intracanal medication. The frequency of positive culture and CFU of each culture were evaluated by ANOVA. RESULTS： The frequency of positive culture was dropped from 73.3% to 46.7% after instrumentation and to 13.3% after medication in the experimental group, while in the control group the frequency was dropped from 73.3% to 20.0% and 26.7% after medication （P=0.9721）. CFU was dropped from 1462.9 to 27.9 after instrumentation and 15.7 after medication, while in the control group CFU was dropped from 1402.8 to 14.0 and 45.1 after medication （P=0.688）. CONCLUSIONS： Jinzhi Hanshuye had good antibacterial effects on anaerobics of infected root canals.

关 键 词：金栀含漱液 根管冲洗 根管消毒 

分 类 号：R781.05[医药卫生—口腔医学]