胃食管反流病的症状评分及内镜下表现的对照研究  

Comparative study on symptom scores of gastroesophageal reflux disease and its endoscopic performance

作　　者：李艳梅[1] 苏秉忠[1] 宋建忠[1] 

机构地区：[1]内蒙古医学院附属医院消化内科,呼和浩特010050

出　　处：《中华消化内镜杂志》2006年第1期7-10,共4页Chinese Journal of Digestive Endoscopy

摘　　要：目的探讨用胃食管反流病(GERD)的症状评分及内镜下表现的对照研究来预测和评估是否有GERD及其程度。方法对500例有胃食管反流症状的患者按症状频率、病期与程度为评分标准进行症状评分,内镜检查是否有反流性食管炎(RE)并分级。比较症状评分与内镜分级的相关性,分析症状评分对GERD的评估价值。200例无症状体检者作为阴性对照。结果GERD症状评分与RE内镜分级呈正相关(r=0·560,P<0·01)。RE组患者的症状评分高于非糜烂性反流病(NERD)组,RE组症状评分≥8分者有81·70%,NERD组为59·35%(P<0·05);RE患者烧心的程度及发作频率、反酸的发作频率与病期重于NERD。GERD组与无反流症状组内镜检查结果比较亦有统计学意义(P<0·01)。结论症状评分是诊断GERD的一个良好的筛选项目。Objective To predict the existence and extent of gastroesophageal reflux disease （GERD） from the symptom scores and endoscopic performance. Methods Among 500 patients with the symptoms of gastroesophageal reflux, each symptom was scored according to the frequency, duration and severity. Each patient performed upper gastrointestinal endoscopy to detect reflux esopha＇gitis （RE） and grade the endoscopic findings, and relativity between then were compared. Two hundred cases without symptom of gastroesophageal reflux were served as control. Results Symptom scores correlated positively with endoscopy grading （ r = 0. 560 ,P 〈 0. 01 ）. The symptom scores of RE group were higher than those of non-erosive reflux disease （NERD） group. There were scored above 8 in 81.70% of RE group,and 59. 35% of in NERD group （P 〈0.05 ）. The difference was significant between the groups of RE and NERD with degree and frenquency of heartburn, frenquency and duration of regurgitation. There was significant difference with endoscopy grading between GERD and control group（ P 〈 0.01 ）. Conclusion Symptom scores may be served as a useful measure in dicoresing GERD.

关 键 词：胃食管反流病 症状 评分 

分 类 号：R571[医药卫生—消化系统]