老年牙根龋患者菌斑致病菌分析  

An analysis of the dental plaque microbiology of root surface caries in elderly patients

作　　者：张廷发[1] 王猛涛[1] 张春梅[2] 杨圣辉[2] 

机构地区：[1]卫生部北京医院口腔科,100730 [2]首都医科大学附属北京口腔医学研究所

出　　处：《中华老年医学杂志》2006年第2期117-119,共3页Chinese Journal of Geriatrics

摘　　要：目的通过对老年人牙根龋菌斑微生物的定量分析,了解牙根龋的相关致病菌。方法选择60～77岁老年患者75例,其中患牙根龋无牙髓及根尖炎症者45例为根龋组,根外露无牙根龋者30例为对照组即无根龋组。两组患者均留取菌斑标本,接种于选择与非选择培养基,培养、分离后,对总菌数,产黑色素菌、链球菌、变形链球菌群、放线菌、乳酸杆菌的菌数及检出率进行对比分析。结果根龋组总菌、总链球菌、放线菌、乳酸杆菌数、产黑色素菌分别为(4.73±0.75)、(3.89±0.89)、(3.24±1.89)、(3.24±1.11)、(2.67±0.70)lg(CFU/ml+1),比无根龋组[(4.17±0.47)、(2.84±1.14)、(2.19±0.11)、(2.43±0.95)、(3.24±0.21)lg(CFU/ml+1)]高,两组比较差异有统计学意义(均为 P<0.05或 P<0.01)。根龋组放线菌、乳酸杆菌的检出率明显高于无根龋组[36例(80.0%)与12例(40.4%),P<0.05;33例(73.3%)与6例(20.2%),P<0.01]。结论老年人牙根龋致龋微生物以放线菌和乳酸杆菌为主。减少或消除菌斑致病菌对牙骨质的刺激,是预防老年人牙根龋的重要措施。Objective To study the microbiology of root surface caries in elderly patients. Methods Seventy-five elderly people （aged 60-77 years） were divided into 2 groups： Control group of patients without root caries （n= 30）and root caries group of patients with root caries without apicitis and pulpitis （n=45）. Plaque samples were collected, cultured in selective and non-selective media. After the bacteria were isolated, the total count and the detection rates and bacterium numbers of porphyromonas, pervotella, streptococcus mutants group, actiomyces and lactobacillus were compared between the groups of control and root caries. Results The count of total bacteria, streptococcus mutants group, actinomyces, lactobacillus and of root caries group were significantly higher that those of the control group （ 4.73 ± 0.75） lg （CFU/ml ＋ 1 ） vs （ 4.17±0.47） lg（ CFU/ml ＋ 1 ）, （3.89±0.89）lg（CFU/ml＋ 1） vs（2.84 ± 1. 14）lg（CFU/ml＋ 1）, （3.24 ± 1.89）lg（CFU/ml＋ 1） vs （2.19±0.11）lg（CFU/ml＋l）, （3.24±1.11）lg（CFU/ml＋1）vs （2.43±0.95）lg（CFU/ml＋l）, （2.67±0.70）lg（CFU/ml＋l）vs （3.24±0.21）lg（CFU/ml＋1）,（P〈0.05 or P〈0.01）. And the positive rate of actinomyces and lactobacillus of root caries group were obviously higher than those of the control group[36（80.0%）vs 12（40.4%） ,P〈0.05 and 33（73.3%）vs 6（20.2%）,P〈 0.01%. Conclusions Actinomyces and lactobacillus are main pathogens of root surface caries in elderly patients.

关 键 词：牙根龋 放线菌科 乳杆菌科 链球菌 变异 

分 类 号：R781.1[医药卫生—口腔医学]