人精浆中五种肿瘤标志物在生殖功能中的意义  

The significance of the five kinds of tumor markers of the seminal plasma in reproduction function

作　　者：徐志强 唐宝松 金丽娟 周德众[2] 

机构地区：[1]抚顺石油一厂职工医院,辽宁113006 [2]中国医科大学第七临床学院(抚顺矿业集团总医院),辽宁113008

出　　处：《中国性科学》2005年第12期3-5,共3页Chinese Journal of Human Sexuality

摘　　要：通过对42名男性精浆中肿瘤标志物的测定,发现精浆中五肿瘤标志物浓度均与其血清浓度不同。CA50和CA19.9浓度的平均值均为血清浓度的300倍,CA125为14倍,CA195为22倍,而AFP的浓度约为血清浓度的1/3。通过对精浆中肿瘤标志物浓度与不育时间的关系、与精液分析结果的关系、与其他因素的关系及与妊娠的关系等进行系统分析的结果表明,精浆中CA125和CA19.9可作为精子生殖功能的标志物,精液中糖类肿瘤标志物浓度增高与临床表现有关,但与精子性质无关;最值得重视的是CA125和CA19.9,为低浓度时,其配偶可发生妊娠。This study through qualitative analyses of the tumor markers in 42 males the seminal plasma, discovered that density of the five kinds of tumor markers in the seminal plasma is different from the density of the blood serum. The average density of CA50, CA 19.9 ,CA 125 and CA 195 is significantly higher than in the blood serum.But the density of AFP is lower than the density of the blood serum. Through the system analysis of the relationship between the density of the seminal plasma in the tumor marker and the time of sterile, the analysis result of the seminal plasma and other factors, and the pregnancy, the result shows the rise of the density of the marker of carbohydrate tumor matkers in the seminal plasma is related with the clinical performance, but has nothing to do with the nature of spermatozoon .The most important is that when CA125 and CA19.9 are in low density, his spouse may pregnancy.

关 键 词：CA125 CA19.9 生育能力 人精浆 肿瘤标志物 

分 类 号：R734.2[医药卫生—肿瘤] R135.1[医药卫生—临床医学]