Phellinus chrysoloma(Fr.) Donk抗肿瘤作用初步研究  

PRELIMINARY INVESTIGATION OF ANTITUMOR EFFECT OF A MACROFUNGUS, PHELLINUS CHRYSOLOMA (FR.) DONK

作　　者：彭烨城[1] 郑维发[2] 陈才法[2] 高晓雯[2] 田桂芬[1] 宗志敏[1] 魏贤勇[1] 

机构地区：[1]中国矿业大学化工学院,221008 [2]江苏省药用植物生物技术重点实验室,221116

出　　处：《中国科技信息》2006年第5期101-102,共2页China Science and Technology Information

摘　　要：本文通过体外细胞毒试验、体内肿瘤细胞抑制试验,研究了Phellinuschrysoloma(Fr.)Donk(P.chrysoloma)丙酮、甲醇、水分级提取物的细胞毒、抗肿瘤活性。结果显示P.chrysoloma丙酮及甲醇提取物可显著抑制S-180细胞的增殖,各级提取物均具有显著抑制S-180肿瘤生长的作用。The cytotoxic and antitumor activities of acetone,methanol and aqueous extracts of Phellinus chrysoloma.（Fr.）Donk was studied.Acetone and methanol extracts of P.chrysoloma showed in vitro cytotoxic activity against S-180 cell lines,All three extracts were highly effective in inhibiting growth of solid tumor induced by S-180 cell line in mice.The experimental results revealed that all extracts of P.chrysoloma possessed significant antitumor activity.

关 键 词：S-180 抗肿瘤 细胞毒 

分 类 号：R730.5[医药卫生—肿瘤]