不同种类无机抗菌剂对口腔致病菌抗菌性能比较及其检测方法探讨  

Evaluation the Ability of Inorganic Antibacterial Agents Against Oral Pathogenic Bacteria: a Method Comparison

作　　者：方明[1] 陈吉华[1] 徐修礼[2] 杨佩红[2] 刘奕[1] 

机构地区：[1]第四军医大学口腔医学院修复科,陕西西安710032 [2]第四军医大学西京医院检验科

出　　处：《口腔医学研究》2006年第1期12-14,共3页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:30371556)

摘　　要：目的:比较无机抗菌剂对口腔致病菌的抗菌活性,并探讨不溶物质的优选测试方法。方法:采用试管液体稀释法和琼脂稀释法测试6种无机抗菌剂对6种口腔常见致病菌的抗菌活性。结果:试管液体稀释法测试结果显著低于琼脂稀释法。受试抗菌剂体外综合抗菌活性从高到低依次为:龙贝无机抗菌粉体、ZnOw AT-83、IONPURE-H、碱式次氯酸镁、ZnOw AT-88、安迪美-AMS2。结论:6种无机抗菌剂对实验菌株均有不同程度的抗菌活性。不溶性物质抗菌活性测试宜用液体稀释法。Objective： To compare the antibacterial activities of different inorganic antibacterial agents on oral pathogenic bacteria, and to evaluate the suitable test method for insoluble materials. Methods： The in vitro antibacterial activities of six commercial inorganic antibacterial agents on six oral pathogenic bacteria were determined by both dilution test and agar dilution test. Results： The results of both dilution test were significantly lower than those of the agar dilution test. Among the tested agents, Longbei inorganic antibiotic powder had the strongest antibacterial activities against tested bacteria, and the followings were ZnO wisker antibacterial complex （ZnOw） AT- 83, IONPURE -H, basic magnesium hypochlorite, ZnOw AT- 88, and Antim -AMS2. Conclusion： All six inorganic antibacterial agents have different antibacterial activities on tested oral pathogenic bacteria. It is suggested to use both dilution test for testing insoluble agents.

关 键 词：无机抗菌剂 口腔致病菌 抗菌活性 液体稀释法 琼脂稀释法 

分 类 号：R781.05[医药卫生—口腔医学]