中药白鲜皮中重金属和农药残留量的分析  

Determination of Heavy Metals and Pesticide Residue of Cortex Dictamni

作　　者：杜程芳[1] 屠鹏飞[1] 欧阳荔[2] 杨彬[2] 

机构地区：[1]北京大学药学院 [2]北京大学医药卫生分析测试中心,北京100083

出　　处：《中国药品标准》2006年第1期12-14,共3页Drug Standards of China

基　　金：基金项目国家"九五"重点科技攻关计划项目基金资助(No.99-929-01-25)

摘　　要：目的：分析白鲜皮药材中重金属和农药残留量,为白鲜皮的质量控制和标准制定提供依据。方法：采用比色法测定总重金属含量,原子吸收法测定Pb、Cd、Cu、As的含量,ICPMS法测定Hg的含量,GC法测定有机氯农药残留量。结果：白鲜皮药材中含总重金属50～100mg/kg,其中Pb0.12～0.54mlg/kg,Cd 0.007～0.219mg/kg,Cu 1.98～22.31mg/kg,As 0.04～0.81mg/kg,Hg 0.02～0.31mg/kg。所有样品中均未检出DDT,少数样品中检出六六六,含量为19.20～130.33μg/kg。结论：白鲜皮药材中含一定量的重金属,其中铜含量较高,其它重金属含量都很低。白鲜皮为野生药材,大部分未检出有机氯农药残留,少数检出六六六,可能来源于土壤污染。Objective ：To analyze the content of heavy metals and pesticide residue of Cortex Dictamni（the root cortexes of Dictamnus dasycarpus）,and supply the reference for the quality control and standard establishment of Cortex Dictamni. Method： The content of total heavy metals was determined by colorimetry. The content of Pd ,Cd ,Cu and As was measured by atomabsorption spectrophotometry. The content of Hg was obtained by the method of ICP-MS,and the content of organic chlorine pesticide residue was determined by gas chromatography. Result：The content of total heavy metals was 50-100mg/kg,ineluding 0, 12-0. 54mg/kg of Pb,0. 007-0. 219mg/kg of Cd, 1.98-22.31mg/kg of Cu,0. 04-0. 81mg/kg of As and 0. 02- 0. 31mg/kg of Hg No DDT was found in all the 13 samples,bur benzene hexachloride （BHC）was detected in a few samples. The content of BHC was 19.20- 130.33μg/kg. Conclusion：Certain amount of heavy metals could be detected in Cortex Dictamni, Among them,the content of Cu was higher than others, Because of the crude samples, no organic chlorine pesticide residue was found in a majority of Cortex Dictamni. The BHC detected in a few samples maybe come from the pollution of soil.

关 键 词：白鲜皮 重金属 农药残留 

分 类 号：R155.57[医药卫生—营养与食品卫生学] R284.1[医药卫生—公共卫生与预防医学]