静舒氧减轻纳曲酮冲击疗法戒断症状不良反应的临床研究  

Clinical Study on Reduction of Withdrawal Symptoms and Side Effects of Rapid and Higher Doses Naltrexone Therapy by Association of Jing Shu Yang

作　　者：王文甫[1] 单飞豹[1] 刘国阳[1] 蒋铁平[1] 陈辞珍[1] 陈碧英[1] 易仁忠[1] 

机构地区：[1]湖南省脑科医院,湖南省自愿戒毒中心,长沙市410007

出　　处：《中国药物滥用防治杂志》2006年第1期19-22,共4页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：湖南省卫生厅资助(C2005059)

摘　　要：目的:了解辅以静舒氧减轻NTX冲击疗法后戒断症状和不良反应。方法:按王氏方法进行NTX冲击疗法,在冲击治疗期间辅以静舒氧,次日再进行一次,共40例。NTX冲击治疗后每天进行戒断症状和不良反应量表评定。并与未用静舒氧者40例进行临床比较分析。结果:辅以静舒氧者冲击治疗期间反应轻,冲击治疗睡眠时间平均缩短2小时,戒断症状和不良反应明显减轻。结论:辅以静舒氧使NTX冲击疗法更趋完善。也为使用NTX不同剂型奠定了基础,很有临床实用价值。Objective： To understand the associate role of Jing Shu Yang in reduction of withdrawal symptoms and side effects of rapid and higher does naltrexone therapy. Methods： To Wang＇s method of rapid and higher doses naltrexone therapy we added Jing Shu Yang for two days as an associate measure in 40 cases. The evaluation of withdrawal symptoms and side effects was carried everyday by special qualification, and its clinical analysis was compared with 40 cases in control, i.e. without the use of Jing Shu Yang. Results： The side effects and withdrawal symptoms were decreased significantly in experimental group with decreasing of average sleeping time for two hours. Conclusion： The association ofJing Shu Yang makes the rapid and higher doses naltrexone therapy more effective and it lays a good foundation for different doses in detoxification with naltrexone also. It has higher clinical value.

关 键 词：NTX冲击疗法 静舒氧 海洛因依赖 戒断症状 不良反应 

分 类 号：R749.64[医药卫生—神经病学与精神病学]