67例胃肠道间质瘤临床病理及免疫组化研究  

Gastrointestinal stromal tumors:A pathomorphologic and immunohistochemical study of 67 cases

作　　者：李潮[1] 宋丁[2] 

机构地区：[1]锦州医学院附属第一医院病理科,辽宁锦州121000 [2]吉林大学中日联谊医院病理科,吉林长春130033

出　　处：《中国实验诊断学》2006年第3期250-252,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨胃肠道间质瘤(gastrointestinal stromal tumor,GIST)的临床病理、免疫组化特点。方法观察67例胃肠道间质瘤形态学特征及免疫组化染色。结果61.2%胃肠道间质瘤发生在小肠,瘤细胞为梭形或上皮样,或两者混合存在,胞浆嗜酸性较弱,免疫组化表型为CD34+,CD117+。结论胃肠道间质瘤有较独特的免疫组化表型,免疫组化可协助鉴别诊断。Objective To investigate the pathological and immunohistochemical features of gastrointestinal stromal tumors（GIST）. Methods 67 cases of GIST were studied by routine stain and immunohistochemistry.Results 61.2% of the tumors originated in the small intestine. The neoplastic cells of GIST were spindle,epithelioid or both in different proportion, have a lesser degree of cytoplasmic eosinophilia. The immunophenotypo of GIST was CD34＋ , CD117＋ . Conclusion GIST is with special immunophentype. The immunnohistochemistry is useful for differential diagnosis.

关 键 词：胃肠道间质瘤 病理 免疫组化 

分 类 号：R735[医药卫生—肿瘤]